2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
- Product Name
- 2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
- CAS No.
- 1210-81-7
- Chemical Name
- 2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
- Synonyms
- ST1936;ST1936,ST-1936;ST 1936 oxalate;ST1936, 10 mM in DMSO;5-Chloro-N,N,2-trimethyl-1H-indole-3-ethanamine;1H-Indole-3-ethanamine, 5-chloro-N,N,2-trimethyl-;5-Chloro-3-[2-(dimethylamino)ethyl]-2-methylindole oxalate;2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
- CBNumber
- CB92750485
- Molecular Formula
- C13H17ClN2
- Formula Weight
- 236.74
- MOL File
- 1210-81-7.mol
2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine Property
- Boiling point:
- 377.0±42.0 °C(Predicted)
- Density
- 1.165±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥5mg/mL (warmed)
- pka
- 16.90±0.30(Predicted)
- form
- powder
- color
- white to beige
N-Bromosuccinimide Price
- Product number
- SML0260
- Product name
- ST1936
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $83.4
- Updated
- 2022/05/15
- Product number
- SML0260
- Product name
- ST1936
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $339
- Updated
- 2022/05/15
- Product number
- 39811
- Product name
- ST1936
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $43
- Updated
- 2026/04/30
- Product number
- 39811
- Product name
- ST1936
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $194
- Updated
- 2026/04/30
- Product number
- 39811
- Product name
- ST1936
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $323
- Updated
- 2026/04/30
2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine Chemical Properties,Usage,Production
Uses
Serotonin 5-HT(6) receptor agonists and antagonists have been proposed as possible useful compounds in the treatment of psychiatric disorders such as depression (1). ST 1936 Oxalate is a 5-HT(6) receptor agonist and may be a potential antidepressant/anti-anhedonic drug (1,2).
in vivo
ST1936 (5, 10, 20 mg/kg; i.p.) increases in a dose dependent manner extracellular dopamine (DA) and NA levels in the prefrontal cortex (PFCX)[4].
ST1936 (5, 10, 20 mg/kg; i.p.) increases extracellular DA and NA levels in the nucleus accumbens (NAc) core. Doses of 10 mg/kg increases dialysate DA (peak: 179%) while higher dose increases both DA and NA dialysates (201% and 231%, respectively). Doses of 5 mg/kg does not produce any effect[4].
IC 50
5-HT6 Receptor: 13 nM (Ki); 5-HT7 Receptor: 168 nM (Ki); 5-HT2B Receptor: 245 nM (Ki); α1-adrenergic receptor: 390 nM (Ki, rat); α2-adrenergic receptor: 300 nM (Ki, rat); α2-adrenergic receptor: 300 nM (Ki, human)
2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine Preparation Products And Raw materials
Raw materials
Preparation Products
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