2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol

Product Name: 2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol
CAS No.: 134179-40-1
Chemical Name: 2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms: TBDMS-PEG5;TBDMS-PEG4-OH;TBDMS-PEG4-alcohol;2-[2-(2-TBDMSO-ethoxy)ethoxy]ethoxy]ethanol;2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol;13,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-sila-1-pentadecanol;3,6,9,12-Tetraoxa-13-silapentadecan-1-ol, 13,13,14,14-tetramethyl-;13,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-sila-1-pentadecanol 97%;2-[2-[2-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]ethoxy]ethoxy]ethanol;2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol
CBNumber: CB92755990
Molecular Formula: C14H32O5Si
Formula Weight: 308.49
MOL File: 134179-40-1.mol

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2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol Property

Density: 0.959 g/mL at 25 °C
refractive index: n20/D1.447
Flash point:: >110℃
storage temp.: Storage temp. 2-8°C
pka: 14.36±0.10(Predicted)
form: Liquid
color: Colorless to light yellow
Boiling point:: 330-338°C/760 mmHg
InChI: InChI=1S/C14H32O5Si/c1-14(2,3)20(4,5)19-13-12-18-11-10-17-9-8-16-7-6-15/h15H,6-13H2,1-5H3
InChIKey: KZFZMISGZPOLJM-UHFFFAOYSA-N
SMILES: C(O)COCCOCCOCCO[Si](C)(C)C(C)(C)C

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Safety

Hazard Codes: T
Risk Statements: 25-38
Safety Statements: 45
RIDADR: UN 2810 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 767778
Product name: 13,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-sila-1-pentadecanol
Purity: 97%
Packaging: 1g
Price: $90
Updated: 2023/06/20

TRC

Product number: T948010
Product name: Tbdms-Peg4-Alcohol
Packaging: 100mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: 4704AQ
Product name: 2,2,3,3-tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
Packaging: 250mg
Price: $131.6
Updated: 2021/12/16

BroadPharm

Product number: BP-21717
Product name: TBDMS-PEG5
Purity: 98%
Packaging: 1g
Price: $280
Updated: 2021/12/16

AK Scientific

Product number: 4704AQ
Product name: 2,2,3,3-tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
Packaging: 5g
Price: $416
Updated: 2021/12/16

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2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol Chemical Properties,Usage,Production

Description

TBDMS-PEG5 is a PEG linker containing a TBDMS alcohol protecting group and a terminal hydroxyl group. TBDMS can be removed in the presence of acetyl chloride. The terminal hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of compounds in aqueous environments.

Uses

TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol Suppliers

China 32 India 1 United Kingdom 1 United States 5 Global 39

Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd

Tel: 037188900765 18037465274
Fax: QQ3430974218
Email: enyawanglei@sina.cn
Country: China
ProdList: 13966
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Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
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Jinan elephant international trading co., LTD

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ProdList: 6355
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Shanghai Yihe Biological Technology Co., Ltd.

Tel: 021-68882955 17721395025
Fax: 021-68882955
Email: 2423903095@qq.com
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Wuxi AppTec

Tel: 022-59987777 13552403979
Email: jia_guoqiang@wuxiapptec.com
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Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
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Xi'an Confluore Biological Technology Co., Ltd.

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Email: 1924344760@qq.com
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ProdList: 4952
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Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
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Country: China
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Zhengzhou Alfa Chemical Co.,Ltd

Tel: +8618530059196
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Country: China
ProdList: 11784
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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View Lastest Price from 2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Tbdms-PEG4-alcohol 134179-40-1
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-27

134179-40-1, 2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanolRelated Search:

TBDMS-PEG4-Acid Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 13,13,14,14-tetramethyl-3,6,9,12-tetraoxa-13-silapentadec-1-yl ester

13,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-sila-1-pentadecanol

2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol

2-[2-(2-TBDMSO-ethoxy)ethoxy]ethoxy]ethanol

2-[2-[2-[2-[(tert-Butyldimethylsilanyl)oxy]ethoxy]ethoxy]ethoxy]ethanol

TBDMS-PEG4-alcohol

TBDMS-PEG5

TBDMS-PEG4-OH

3,6,9,12-Tetraoxa-13-silapentadecan-1-ol, 13,13,14,14-tetramethyl-

13,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-sila-1-pentadecanol 97%

2-[2-[2-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]ethoxy]ethoxy]ethanol

134179-40-1

C14H32O5Si