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TETRAETHYL PYROPHOSPHITE

Product Name
TETRAETHYL PYROPHOSPHITE
CAS No.
21646-99-1
Chemical Name
TETRAETHYL PYROPHOSPHITE
Synonyms
TETRAETHYL PYROPHOSPHITE;Oxybis(diethoxyphosphine);Bis(diethoxyphosphino) ether;Tetraethyl pyrophosphite 96%;iethoxyphosphanyldiethylphosphite;Tetraethyl pyrophosphite,93%,tech.;Diphosphorous acid tetraethyl ester;TETRAETHYL PYROPHOSPHITE, TECH., 93%;Bis(phosphorous acid diethyl)anhydride;Oxybis(phosphonous acid diethyl) ester
CBNumber
CB9279595
Molecular Formula
C8H20O5P2
Formula Weight
258.19
MOL File
21646-99-1.mol
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TETRAETHYL PYROPHOSPHITE Property

Boiling point:
79-81 °C/1 mmHg (lit.)
Density 
1.057 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.434(lit.)
Flash point:
>230 °F
solubility 
Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
form 
Oil
color 
Colourless
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
155411
Product name
Tetraethyl pyrophosphite
Purity
96%
Packaging
5g
Price
$183
Updated
2024/03/01
TRC
Product number
T303765
Product name
Tetraethyl pyrophosphite
Packaging
500mg
Price
$95
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156978
Product name
TETRAETHYL PYROPHOSPHITE
Purity
95.00%
Packaging
5G
Price
$927.15
Updated
2021/12/16
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TETRAETHYL PYROPHOSPHITE Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Tetraethyl Pyrophosphite is used as a reagent in the preparation of peptides and in the phosphonylation of carbonyl compounds.

Uses

The product can be used as a reagent for peptide synthesis.

Application

Tetraethyl pyrophosphite can be used in peptide synthesis; phosphonylation of ketones, aldehydes, and perfluoroalkyl iodides.

Preparation

The most convenient method involves the reaction of diethyl phosphite with diethyl  phosphorochloridite. Diethyl phosphorochloridite (223 g) is added rapidly to a solution of diethyl phosphite (138 g) and  triethylamine (101 g) in benzene (200 ml). The mixture is filtered and the benzene removed by distillation at reduced  pressure. The product is isolated by further distillation at reduced pressure (79-81 °C/0.15 mmHg) in 41% yield.

TETRAETHYL PYROPHOSPHITE Preparation Products And Raw materials

Raw materials

Preparation Products

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TETRAETHYL PYROPHOSPHITE Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29810
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-81139210 +86-18192627656
Fax
+86-29-88380327
Email
1059@dideu.com
Country
China
ProdList
3003
Advantage
58
Zhengzhou Alpha Chemical Co. LTD
Tel
0371-0371-53732842 13383863444
Fax
QQ:3002612166
Email
3002612166@qq.com
Country
China
ProdList
10024
Advantage
58
Hubei Shishun Biotechnology Co. Ltd
Tel
027-59223025 15107168801
Fax
027-59223025
Email
1718480011@qq.com
Country
China
ProdList
9847
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
029-029-81148696 18161915376
Email
1040@dideu.com
Country
China
ProdList
9998
Advantage
58
Shanghai Yingxin laboratory equipment Co., Ltd
Tel
021-021-59178156 15300768757
Email
359382369@qq.com
Country
China
ProdList
10674
Advantage
58
Shanghai Guchen Biotechnology Co., LTD
Tel
021-34675735 19147740836
Email
1986399151@qq.com
Country
China
ProdList
9844
Advantage
58
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View Lastest Price from TETRAETHYL PYROPHOSPHITE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Tetraethyl pyrophosphite 21646-99-1
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-01-16
Career Henan Chemical Co
Product
TETRAETHYL PYROPHOSPHITE 21646-99-1
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-21

21646-99-1, TETRAETHYL PYROPHOSPHITERelated Search:


  • TETRAETHYL PYROPHOSPHITE
  • TETRAETHYL PYROPHOSPHITE, TECH., 93%
  • Bis(diethoxyphosphino) ether
  • Bis(phosphorous acid diethyl)anhydride
  • Diphosphorous acid tetraethyl ester
  • Oxybis(diethoxyphosphine)
  • Oxybis(phosphonous acid diethyl) ester
  • Tetraethyl pyrophosphite,93%,tech.
  • Tetraethyl pyrophosphite 96%
  • Diphosphorous acid, P,P,P',P'-tetraethyl ester
  • iethoxyphosphanyldiethylphosphite
  • 21646-99-1
  • C8H20O5P2
  • C2H5O2POPOC2H52
  • Building Blocks
  • Organic Phosphates/Phosphites
  • Phosphorus Compounds
  • Organic Building Blocks
  • Organic Building Blocks
  • Organic Phosphates/Phosphites
  • Phosphorus Compounds