1,2-DIOLEOYL-SN-GLYCERO-3-[N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID SUCCINYL] (NICKEL SALT)
- Product Name
- 1,2-DIOLEOYL-SN-GLYCERO-3-[N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID SUCCINYL] (NICKEL SALT)
- CAS No.
- 231615-77-3
- Chemical Name
- 1,2-DIOLEOYL-SN-GLYCERO-3-[N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID SUCCINYL] (NICKEL SALT)
- Synonyms
- 18:1 DGS-NTA (NI);DOGS-NTA (NICKEL);1,2-DIOLEOYL-SN-GLYCERO-3-[N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID SUCCINYL] (NICKEL SALT);1,2-DIOLEOYL-SN-GLYCERO-3-[(N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID)SUCCINYL] (NICKEL SALT);18:1 DGS-NTA(NI)
- CBNumber
- CB9282216
- Molecular Formula
- C53H92N2NiO15
- Formula Weight
- 1056.01
- MOL File
- Mol file
1,2-DIOLEOYL-SN-GLYCERO-3-[N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID SUCCINYL] (NICKEL SALT) Property
- storage temp.
- -20°C
- form
- powder
Safety
- WGK Germany
- WGK 3
- Storage Class
- 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects - Hazard Classifications
- Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1 Oral
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
1,2-DIOLEOYL-SN-GLYCERO-3-[N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID SUCCINYL] (NICKEL SALT) Chemical Properties,Usage,Production
Uses
18:1 DGS-NTA(Ni) has been used for the preparation of liposomes.
Biological Activity
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is useful in structural biology especially to bind recombinant histidine tagged proteins. Though useful, being nanoparticulate it has stability problems in biological samples. So NTA-lipid conjugate is majorly used as liposomes or as a coating to nanoparticle. DGS-NTA (Ni) based nanosize multillamelar vesicles (NMVs) are potent vaccine delivery system.
1,2-DIOLEOYL-SN-GLYCERO-3-[N-(5-AMINO-1-CARBOXYPENTYL)IMINODIACETIC ACID SUCCINYL] (NICKEL SALT) Preparation Products And Raw materials
Raw materials
Preparation Products
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