N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE
- Product Name
- N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE
- CAS No.
- 10429-82-0
- Chemical Name
- N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE
- Synonyms
- N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine;eMbito;embitol;BUTTPARK 146\50-40;N-BENZYL-BIS(2-CHLOROETHYL)AMINE HCL;N-Benzyl-N,N-bis(2-chloroethyl)amine;N,N-Di(2-Chloroethyl) Benzylamine HCl;N Benzyl N, N Bis (2 chloroéthyl) AMine;N-BENZYL-N,N-BIS(2-CHLOROETHYL)AMINE HCL;N,N-Bis-(2-chloroethyl)-N-benzylamine.HCl
- CBNumber
- CB9284715
- Molecular Formula
- C11H16Cl3N
- Formula Weight
- 268.61
- MOL File
- 10429-82-0.mol
N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE Property
- Melting point:
- 134-136°
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
- form
- Solid
- color
- Off-White to Pale Beige
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C11H15Cl2N.ClH/c12-6-8-14(9-7-13)10-11-4-2-1-3-5-11;/h1-5H,6-10H2;1H
- InChIKey
- AZRWNJFEUSHORT-UHFFFAOYSA-N
- SMILES
- N(CCCl)(CCCl)CC1C=CC=CC=1.Cl
- CAS DataBase Reference
- 10429-82-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- RIDADR
- UN2923
- HazardClass
- IRRITANT
- HS Code
- 29214990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B5445
- Product name
- N-Benzyl-N,N-bis(2-chloroethyl)amine Hydrochloride
- Packaging
- 1G
- Price
- $57
- Updated
- 2025/07/31
- Product number
- B5445
- Product name
- N-Benzyl-N,N-bis(2-chloroethyl)amine Hydrochloride
- Packaging
- 5G
- Price
- $170
- Updated
- 2025/07/31
- Product number
- B233788
- Product name
- N-Benzyl-bis(2-chloroethyl)amineHydrochloride
- Packaging
- 500mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB31792
- Product name
- N,N-Bis(2-chloroethyl)benzenemethanamine HCl
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- OR24559
- Product name
- Benzyl[bis(2-chloroethyl)]amine hydrochloride
- Packaging
- 250mg
- Price
- $71
- Updated
- 2021/12/16
N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
N-Benzyl-bis(2-chloroethyl)amine Hydrochloride can be used to prepare RSV F protein inhibitors.
Synthesis
101-32-6
10429-82-0
General procedure for the synthesis of N-benzyl-bis(2-chloroethyl)amine hydrochloride from 2,2'-(benzylimino)diethanol: A solution of sulfur dichloride (35.8 mL, 482 mmol) in anhydrous dichloromethane (60 mL) was added slowly and dropwise to a dichloromethane (200 mL) solution of 2,2'-(benzylimino)diethanol (obtained in step a, 31.4 g, 160 mmol). mL) in a cold solution of methylene chloride (200 mL). The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the solvent was removed to dryness by rotary evaporation to afford N-benzyl-bis(2-chloroethyl)amine hydrochloride (47.2 g, 100% yield), and the product was used directly in the next step without further purification.HPLC-MS (Method A): retention time, 2.34 min; ESI-MS m/z, 262 (M + 1).
References
[1] Patent: WO2017/16669, 2017, A1. Location in patent: Page/Page column 201
[2] Patent: EP970046, 2003, B1. Location in patent: Page 46
[3] Patent: US6342508, 2002, B1. Location in patent: Page column 59
[4] European Journal of Medicinal Chemistry, 2014, vol. 75, p. 11 - 20
[5] Chemical Communications, 2002, # 23, p. 2840 - 2841
N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE manufacturers
- Product
- N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE 10429-82-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2018-08-21
- Product
- N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE 10429-82-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2018-08-21