Appearance
ChemicalBook > CAS DataBase List > 2,3-Naphthalenedicarboxylic Anhydride

2,3-Naphthalenedicarboxylic Anhydride

Appearance
Product Name
2,3-Naphthalenedicarboxylic Anhydride
CAS No.
716-39-2
Chemical Name
2,3-Naphthalenedicarboxylic Anhydride
Synonyms
EA253;2,3-NAPHTHALI;2,3-NAPHTHALIC ANHYDRIDE;naphtho[2,3-c]furan-1,3-dione;benzo[f][2]benzofuran-1,3-dione;benzo[f]isobenzofuran-1,3-quinone;2,3-Napthalenedicarboxycanhydride;2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE;2,3-NaphthalenedicarboxylicAnhydride>1,3-Dihydronaphtho[2,3-c]furan-1,3-dione
CBNumber
CB9286597
Molecular Formula
C12H6O3
Formula Weight
198.17
MOL File
716-39-2.mol
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2,3-Naphthalenedicarboxylic Anhydride Property

Melting point:
246 °C
Boiling point:
275-280 °C(Press: 100 Torr)
Density 
1.449±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
color 
Pale Beige
Stability:
Moisture Sensitive
InChI
InChI=1S/C12H6O3/c13-11-9-5-7-3-1-2-4-8(7)6-10(9)12(14)15-11/h1-6H
InChIKey
IZJDCINIYIMFGX-UHFFFAOYSA-N
SMILES
O1C(=O)C2=CC3C(C=C2C1=O)=CC=CC=3
EPA Substance Registry System
Naphtho[2,3-c]furan-1,3-dione (716-39-2)
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Safety

Safety Statements 
22-24/25
HS Code 
2917.39.7000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S876682
Product name
2,3-NAPHTHALIC ANHYDRIDE
Purity
Aldrich
Packaging
50mg
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
N0530
Product name
2,3-Naphthalenedicarboxylic Anhydride
Purity
>95.0%(GC)(T)
Packaging
25g
Price
$192
Updated
2024/03/01
TCI Chemical
Product number
N0530
Product name
2,3-Naphthalenedicarboxylic Anhydride
Purity
>95.0%(GC)(T)
Packaging
250g
Price
$772
Updated
2024/03/01
TRC
Product number
N363000
Product name
2,3-NAPHTHALIC ANHYDRIDE
Packaging
5g
Price
$100
Updated
2021/12/16
TRC
Product number
N363000
Product name
2,3-NAPHTHALIC ANHYDRIDE
Packaging
1g
Price
$80
Updated
2021/12/16
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2,3-Naphthalenedicarboxylic Anhydride Chemical Properties,Usage,Production

Appearance

2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE is a pale Beige Solid.

Description

A few years ago, the product was still synthesized from the corresponding diacid, but in recent years, it has been difficult to find the shadow of the diacid in the market, and the sales of this product have been repeatedly restricted, resulting in high prices.

Uses

2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.

Preparation

Add anhydrous tetrahydrofuran (its mass ratio to maleic anhydride is 1.5:1), cat-1 (0.05 mole), maleic anhydride (1 mole), and o-phthalaldehyde (1.5 mole) to the reactor. After adding triethylamine (5 moles), adjust the temperature below -40°C. Silicon tetrachloride (4 moles) was added dropwise to the reaction system and the reaction was placed at -40 °C for 4 h. The mixture was heated to reflux for 20 h. After the end of the reaction, concentrating the solution to a certain concentration with diatomaceous earth filtration. A light yellow solid, namely 2,3-Naphthalenedicarboxylic Anhydride, is obtained by precipitation, filtration, recrystallization and drying. Its yield reaches 88%.

2,3-Naphthalenedicarboxylic Anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-Naphthalenedicarboxylic Anhydride Suppliers

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View Lastest Price from 2,3-Naphthalenedicarboxylic Anhydride manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,3-Naphthalenedicarboxylic Anhydride 716-39-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-04-27
Henan Research New Materials Co., Ltd.
Product
2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 716-39-2
Price
US $0.00/KG
Min. Order
1KG
Purity
96%
Supply Ability
1000000KG
Release date
2021-05-20
Career Henan Chemical Co
Product
2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 716-39-2
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
ask
Release date
2018-12-20

716-39-2, 2,3-Naphthalenedicarboxylic AnhydrideRelated Search:

2,3-Naphthalenedicarboxylic Anhydride 2,3-ANTHRACENEDICARBOXYLIC ANHYDRIDE 1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 4,5-Dichloro-1,8-naphthalenedicarboxylic anhydride 4-CHLORO-1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE-4-POTASSIUM SULFONATE,4-Potassiosulfo-1,8-naphthalenedicarboxylic anhydride 4-BROMO-1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 4-BROMO-1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 3-Nitro-1,8-naphthalenedicarboxylic anhydride 3-Hydroxy-1,8-naphthalic anhydride 3,4-DIHYDRO-1,2-NAPHTHALENEDICARBOXYLIC ANHYDRIDE ---YELLOWISH CRYSTALLINE POWDER---,3,4-DIHYDRO-1,2-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 4-Hydroxy-1,8-naphthalenedicarboxylic anhydride 4-Amino-1,8-naphthalenedicarboxylic anhydride 4-Nitro-1,8-naphthalenedicarboxylic anhydride 1-PHENYL-2 3-NAPHTHALENEDICARBOXYLIC 1,2-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 1-PHENYL-2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE AKOS 92363

  • 2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE
  • 1,3-Dihydronaphtho[2,3-c]furan-1,3-dione
  • benzo[f][2]benzofuran-1,3-dione
  • benzo[f]isobenzofuran-1,3-quinone
  • 2,3,NAPHTHALENEDICARBOXYLIC ACIDANHYDRIDE
  • naphtho[2,3-c]furan-1,3-dione
  • 2,3-NAPHTHALI
  • 2,3-NAPHTHALIC ANHYDRIDE
  • 2,3-NaphthalenedicarboxylicAnhydride&gt
  • 2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE ISO 9001：2015 REACH
  • EA253
  • 2,3-Napthalenedicarboxycanhydride
  • 716-39-2
  • Exciton Chirality CD Method (for Primary Amino Groups)
  • Enantiomer Excess & Absolute Conefiguration Determination
  • Absolute Conefiguration Determination (Exciton Chirality CD Method)
  • Absolute Configuration Determination (Exciton Chirality CD Method)
  • Analytical Chemistry
  • Enantiomer Excess & Absolute Configuration Determination
  • Exciton Chirality CD Method (for Primary Amino Groups)