ChemicalBook > CAS DataBase List > N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide

N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide

Product Name
N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide
CAS No.
1580000-17-4
Chemical Name
N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide
Synonyms
OS-3-106;OS-3-106 >=98% (HPLC);OS-3-106, 10 mM in DMSO;N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide;Benzamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-4-(4-thiazolyl)-;N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-4-(1,3-thiazol-4-yl)benzamide;Inhibitor,inhibit,Dopamine Receptor,HEK 293 cells,self-administration,arylamide phenylpiperazine,OS 3 106,psychostimulant addiction,cocaine,sucrose,OS3106
CBNumber
CB92973107
Molecular Formula
C25H30N4O2S
Formula Weight
450.6
MOL File
1580000-17-4.mol
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N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Property

Boiling point:
671.3±55.0 °C(Predicted)
Density 
1.185±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
14.22±0.46(Predicted)
color 
Off-white to light yellow
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC43080
Product name
OS-3-106
Purity
>98%
Packaging
250mg
Price
$950
Updated
2021/12/16
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N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Chemical Properties,Usage,Production

Uses

OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 can be used for psychoactivator addiction research[1].

IC 50

D3 Receptor: 0.2 nM (Ki); D2 Receptor

References

[1] Cheung TH, et al. Reduction of cocaine self-administration and D3 receptor-mediated behavior by two novel dopamine D3 receptor-selective partial agonists, OS-3-106 and WW-III-55. J Pharmacol Exp Ther. 2013 Nov;347(2):410-23. DOI:10.1124/jpet.112.202911

N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Suppliers

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1580000-17-4, N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamideRelated Search:


  • N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide
  • OS-3-106
  • Benzamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-4-(4-thiazolyl)-
  • N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-4-(1,3-thiazol-4-yl)benzamide
  • OS-3-106 >=98% (HPLC)
  • Inhibitor,inhibit,Dopamine Receptor,HEK 293 cells,self-administration,arylamide phenylpiperazine,OS 3 106,psychostimulant addiction,cocaine,sucrose,OS3106
  • OS-3-106, 10 mM in DMSO
  • 1580000-17-4