ChemicalBook > CAS DataBase List > 2-BROMO-5-CHLORO-4-METHYL-ANILINE

2-BROMO-5-CHLORO-4-METHYL-ANILINE

Product Name
2-BROMO-5-CHLORO-4-METHYL-ANILINE
CAS No.
102170-52-5
Chemical Name
2-BROMO-5-CHLORO-4-METHYL-ANILINE
Synonyms
4-Amino-5-bromo-2-chlorotoluene;2-chloro-5-bromo-4-aminotoluene;2-BROMO-5-CHLORO-4-METHYL-ANILINE;2-bromo-5-chloro-4-methylbenzenamine;2-Bromo-5-chloro-4-methyl-phenylamine;Benzenamine, 2-bromo-5-chloro-4-methyl-
CBNumber
CB9300176
Molecular Formula
C7H7BrClN
Formula Weight
220.49
MOL File
102170-52-5.mol
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2-BROMO-5-CHLORO-4-METHYL-ANILINE Property

Melting point:
90 °C
Boiling point:
281.3±35.0 °C(Predicted)
Density 
1.619±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
1.91±0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C7H7BrClN/c1-4-2-5(8)7(10)3-6(4)9/h2-3H,10H2,1H3
InChIKey
ULCBEYQOSOVMMA-UHFFFAOYSA-N
SMILES
C1(N)=CC(Cl)=C(C)C=C1Br
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Safety

Hazard Codes 
Xi
HS Code 
2921420090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B821088
Product name
2-Bromo-5-chloro-4-methylaniline
Packaging
50mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
X8594
Product name
2-Bromo-5-chloro-4-methylaniline
Packaging
250mg
Price
$97
Updated
2021/12/16
Matrix Scientific
Product number
140132
Product name
2-Bromo-5-chloro-4-methylaniline
Purity
95%+
Packaging
1g
Price
$114
Updated
2021/12/16
AK Scientific
Product number
X8594
Product name
2-Bromo-5-chloro-4-methylaniline
Packaging
1g
Price
$145
Updated
2021/12/16
Apolloscientific
Product number
OR59373
Product name
2-Bromo-5-chloro-4-methylaniline
Packaging
1g
Price
$163
Updated
2021/12/16
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2-BROMO-5-CHLORO-4-METHYL-ANILINE Chemical Properties,Usage,Production

Synthesis

95-74-9

102170-52-5

Example 4: (5-Chloro-2-((E)-3-(3-(4-fluorophenyl)-3,8-diazanaphthalen-1-yl)-3-oxopropenyl)-4-methylphenyl)urea; a) Synthesis of 2-bromo-5-chloro-4-methylaniline; 3-chloro-4-methylaniline (20.0 g, 0.141 mol) was dissolved in dichloromethane (200 mL) and a 5 minute A solution of N-bromosuccinimide (NBS, 25.1 g, 0.141 mol) in dichloromethane (800 mL) was added slowly over 5 min. The reaction mixture was stirred at room temperature for 5 minutes. Subsequently, the reaction solution was concentrated to about 200 mL and diluted with hexane (1000 mL). The precipitate was collected by filtration, and the filtrate was concentrated and dried and purified by silica gel column chromatography (eluent: hexane/tert-butyl methyl ether, 10:1) to afford the title compound as yellow crystals (12.3 g, 40% yield). A second title compound (7.5 g, 24% yield) was obtained by re-chromatographing the mixed grades.1H-NMR (400 MHz, DMSO-d6) δ (ppm): 2.13 (s, 3H); 5.32 (s, 2H, NH2); 6.81 (s, 1H); 7.31 (s, 1H). Mass spectra (m/z) ES+: 221 (100, [M]+); 219 (80); 184 (35); 140 (100); 104 (50); 77 (65); 52 (58); 51 (60).

References

[1] Patent: WO2005/103054, 2005, A2. Location in patent: Page/Page column 71
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 17, p. 3692 - 3702

2-BROMO-5-CHLORO-4-METHYL-ANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-5-CHLORO-4-METHYL-ANILINE Suppliers

China 47 India 1 United Kingdom 2 United States 12 Global 62
Shanghai Zhixia Chemical Technology Co., LTD
Tel
15216847143 18321145570
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1458509898@qq.com
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China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
Email
sales8178@energy-chemical.com
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China
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44801
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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86-027-87531808
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sales@chemwish.com
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China
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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021-50795055
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sales@accelachem.com
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China
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Wuhan TCASChem Technology Co., Ltd.
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027-86697669 13986148687
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86-027-86697669
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sales@tcaschem.com
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 17798518460
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(1)02557626880
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cfzhang@aikonchem.com
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China
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19913
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9ding chemical ( Shanghai) Limited
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4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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18209
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Shanghai Sainty Biotechnology Co., Ltd.
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021-58957915 17721108391
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QQ: 907522080
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907522080@qq.com
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China
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996
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SuZhou ShiYa Biopharmaceuticals, Inc.
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0512-0512-52358471 17715136450
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05125235 6881
Email
sales@shiyabiopharm.com
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China
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View Lastest Price from 2-BROMO-5-CHLORO-4-METHYL-ANILINE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2-Bromo-5-chloro-4-methylaniline 102170-52-5
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-26

102170-52-5, 2-BROMO-5-CHLORO-4-METHYL-ANILINERelated Search:

5-BROMO-2-CHLOROTOLUENE 2-Chlorotoluene 4-Bromo-3-chloro-2-methylaniline 4-Bromo-2-chloro-6-methylaniline 4-(1,3-BENZOTHIAZOL-2-YL)-2,6-DIBROMO-3-CHLOROANILINE 2,6-DIBROMO-3-CHLORO-4-[1,3]OXAZOLO[4,5-B]PYRIDIN-2-YLANILINE 2-BROMO-5-CHLORO-4-METHYL-ANILINE 3-CHLORO-2,6-DIBROMO-4-METHYLANILINE 3-Chloro-2,6-dibromo-4-methylphenylisothiocyanate N-(2,6-DIBROMO-3-CHLORO-4-METHYLPHENYL)OXO(DIPHENYL)PHOSPHORANECARBOTHIOAMIDE

  • 2-BROMO-5-CHLORO-4-METHYL-ANILINE
  • 2-Bromo-5-chloro-4-methyl-phenylamine
  • 4-Amino-5-bromo-2-chlorotoluene
  • Benzenamine, 2-bromo-5-chloro-4-methyl-
  • 2-bromo-5-chloro-4-methylbenzenamine
  • 2-chloro-5-bromo-4-aminotoluene
  • 102170-52-5
  • Amines
  • blocks
  • Bromides