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GSK-239512

Product Name
GSK-239512
CAS No.
720691-69-0
Chemical Name
GSK-239512
Synonyms
GSK-239512;GSK-239512 720691-69-0;GSK-239512, 10 mM in DMSO;2-Pyrrolidinone, 1-[6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl]-;1-(6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)pyridin-3-yl)pyrrolidin-2-one
CBNumber
CB93032889
Molecular Formula
C23H27N3O2
Formula Weight
377.48
MOL File
720691-69-0.mol
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GSK-239512 Property

Boiling point:
607.6±55.0 °C(Predicted)
Density 
1.239±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
9.02±0.10(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Crysdot
Product number
CD11067408
Product name
1-(6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)pyridin-3-yl)pyrrolidin-2-one
Purity
95+%
Packaging
100mg
Price
$406
Updated
2021/12/16
Alichem
Product number
720691690
Product name
1-(6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)pyridin-3-yl)pyrrolidin-2-one
Packaging
100mg
Price
$434.42
Updated
2021/12/16
Alichem
Product number
720691690
Product name
1-(6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)pyridin-3-yl)pyrrolidin-2-one
Packaging
250mg
Price
$649
Updated
2021/12/16
Crysdot
Product number
CD11067408
Product name
1-(6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)pyridin-3-yl)pyrrolidin-2-one
Purity
95+%
Packaging
250mg
Price
$649
Updated
2021/12/16
Crysdot
Product number
CD11067408
Product name
1-(6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)pyridin-3-yl)pyrrolidin-2-one
Purity
95+%
Packaging
1g
Price
$1622
Updated
2021/12/16
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GSK-239512 Chemical Properties,Usage,Production

Uses

GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD)[1].

IC 50

H3 receptor

References

[1] Grove RA, et, al. A randomized, double-blind, placebo-controlled, 16-week study of the H3 receptor antagonist, GSK239512 as a monotherapy in subjects with mild-to-moderate Alzheimer's disease. Curr Alzheimer Res. 2014 Jan;11(1):47-58. DOI:10.2174/1567205010666131212110148

GSK-239512 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK-239512 Suppliers

China 23 India 1 United Kingdom 1 United States 4 Global 29
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
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720691-69-0, GSK-239512Related Search:


  • GSK-239512
  • 1-(6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)pyridin-3-yl)pyrrolidin-2-one
  • GSK-239512 720691-69-0
  • 2-Pyrrolidinone, 1-[6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl]-
  • GSK-239512, 10 mM in DMSO
  • 720691-69-0