ChemicalBook > CAS DataBase List > 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

Product Name
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
CAS No.
174672-06-1
Chemical Name
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
Synonyms
AN-2718;5-Chloro-2,1-benzoxaborol-1(3H)-ol;5-chlorobenzo[c][1,2]oxaborol-1(3H)-ol;Inhibitor,AN2718,AN 2718,Fungal,AN-2718,inhibit;5-Chloro-1,3-dihydro-2,1-benzoxaborol-1-ol, 95%;5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole;2,1-Benzoxaborole, 5-chloro-1,3-dihydro-1-hydroxy-
CBNumber
CB93036665
Molecular Formula
C7H6BClO2
Formula Weight
168.39
MOL File
174672-06-1.mol
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5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole Property

Melting point:
150-154 °C
Boiling point:
273.2±50.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL
form 
A crystalline solid
pka
6.60±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20708
Product name
AN2718
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
20708
Product name
AN2718
Purity
≥98%
Packaging
5mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
20708
Product name
AN2718
Purity
≥98%
Packaging
10mg
Price
$283
Updated
2024/03/01
Cayman Chemical
Product number
20708
Product name
AN2718
Purity
≥98%
Packaging
25mg
Price
$573
Updated
2024/03/01
Biorbyt Ltd
Product number
orb572891
Product name
AN2718
Packaging
100mg
Price
$606.9
Updated
2021/12/16
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5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole Chemical Properties,Usage,Production

Biological Activity

AN-2718 inhibits the growth of fungi by inhibiting protein synthesis through the OBORT mechanism.

in vitro

AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus , and from yeasts, C. albicans , with an IC 50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T. mentagrophytes .

target

Fungal.

5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole Suppliers

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174672-06-1, 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaboroleRelated Search:

Isopropylmagnesium chloride lithium chloride complex 1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-7-carboxylic acid 6-(hydroxymethyl)benzo[c][1,2]oxaborol-1(3H)-ol 2,1-Benzoxaborole,1,3-dihydro-1-hydroxy-6-Methoxy 6-chlorobenzo[c][1,2]oxaborol-1(3H)-ol 1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-5-carbonitrile

  • 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
  • AN-2718
  • 5-Chloro-1,3-dihydro-2,1-benzoxaborol-1-ol, 95%
  • 5-chlorobenzo[c][1,2]oxaborol-1(3H)-ol
  • 5-Chloro-2,1-benzoxaborol-1(3H)-ol
  • 2,1-Benzoxaborole, 5-chloro-1,3-dihydro-1-hydroxy-
  • Inhibitor,AN2718,AN 2718,Fungal,AN-2718,inhibit
  • 174672-06-1
  • API