Kansuinine B

Product Name: Kansuinine B
CAS No.: 57685-46-8
Chemical Name: Kansuinine B
Synonyms: Kansuinin B;Kansuinine B;Kansuinine B,SARS coronavirus,Interleukin Related,SARS-CoV,Inhibitor,inhibit;(1aS,4R,5S,7R,7aS,8R,9R,10S,10aS,12S,12aS)-8,10a-Diacetoxy-4,9,10-trihydroxy-2,2,9,12-tetramethyl-6-methylene-3,11-dioxotetradecahydro-2H-cyclopenta[5,6]cyclododeca[1,2-b]oxirene-5,7-diyl dibenzoate;2H-Cyclopenta[5,6]cyclododec[1,2-b]oxirene-3,11(1aH,4H)-dione, 8,10a-bis(acetyloxy)-5,7-bis(benzoyloxy)decahydro-4,9,10-trihydroxy-2,2,9,12-tetramethyl-6-methylene-, (1aS,4R,5S,7R,7aS,8R,9R,10S,10aS,12S,12aS)-
CBNumber: CB93037349
Molecular Formula: C38H42O14
Formula Weight: 722.73
MOL File: 57685-46-8.mol

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Kansuinine B Property

storage temp.: 4°C, away from moisture
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN92866
Product name: KansuinineB
Packaging: 5mg
Price: $338
Updated: 2021/12/16

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Kansuinine B Chemical Properties,Usage,Production

Description

Kansuinine B shows cytotoxic activity. Kansuinine B shows analgesic activity. 3. Treatment with kansuinine B and kansuinine A represents a novel method to block the IL-6-induced effects.

Uses

Kansuinine B inhibits IL-6-induced Stat3 activation. Kansuinine B possesses anti-viral activity and could be used in the study for COVID-19[1][2][3].

Definition

ChEBI: Kansuinine B is a benzoate ester.

target

IL Receptor | STAT | ERK | MEK

References

[1] Jong Sun Chang, et al. Kansuinine A and Kansuinine B from Euphorbia kansui L. inhibit IL-6-induced Stat3 activation. Planta Med. 2010 Oct;76(14):1544-9. DOI:10.1055/s-0030-1249805
[2] Xiaoyun Shu, et al. Bioassay-guided separation of the proinflammatory constituents from the roots of Euphorbia kansui. J Nat Med. 2010 Jan;64(1):98-103. DOI:10.1007/s11418-009-0366-0
[3] YASER DAANIAL , et al. PROMISING COMPOUNDS FOR TREATMENT OF COVID-19. VAWKUM Transactions on Computer Sciences, ISSN(e):2308-8168, ISSN(p): 2411-6335. Volume 17, Number 1, January-June, 2020.

Kansuinine B Preparation Products And Raw materials

Raw materials

Preparation Products

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Kansuinine B Suppliers

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57685-46-8, Kansuinine BRelated Search:

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Kansuinine B

Kansuinin B

2H-Cyclopenta[5,6]cyclododec[1,2-b]oxirene-3,11(1aH,4H)-dione, 8,10a-bis(acetyloxy)-5,7-bis(benzoyloxy)decahydro-4,9,10-trihydroxy-2,2,9,12-tetramethyl-6-methylene-, (1aS,4R,5S,7R,7aS,8R,9R,10S,10aS,12S,12aS)-

Kansuinine B,SARS coronavirus,Interleukin Related,SARS-CoV,Inhibitor,inhibit

(1aS,4R,5S,7R,7aS,8R,9R,10S,10aS,12S,12aS)-8,10a-Diacetoxy-4,9,10-trihydroxy-2,2,9,12-tetramethyl-6-methylene-3,11-dioxotetradecahydro-2H-cyclopenta[5,6]cyclododeca[1,2-b]oxirene-5,7-diyl dibenzoate

57685-46-8

C38H42O14