Lefamulin

Product Name: Lefamulin
CAS No.: 1061337-51-6
Chemical Name: Lefamulin
Synonyms: 2-[[(1R,2R,4R)-4-Amino-2-hydroxycyclohexyl]thio]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester;BC 3781;Lefamulin;Lefamulin(BC-3781);Lefamulin, 10 mM in DMSO;(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate;Acetic acid, 2-[[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
CBNumber: CB93039318
Molecular Formula: C28H45NO5S
Formula Weight: 507.73
MOL File: 1061337-51-6.mol

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Lefamulin Property

Boiling point:: 618.6±55.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 16 mg/mL; DMSO: 12 mg/mL; Ethanol: 3 mg/mL; PBS (pH 7.2): 0.25 mg/mL
form: A solid
pka: 14.45±0.60(Predicted)
color: White to off-white
InChIKey: KPVIXBKIJXZQJX-FCEONZPQSA-N
SMILES: C(O[C@@H]1C[C@](C=C)(C)[C@@H](O)[C@H](C)[C@@]23CC[C@@H](C)[C@]1(C)[C@]2([H])C(=O)CC3)(=O)CS[C@@H]1CC[C@@H](N)C[C@H]1O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H411Toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

DC Chemicals

Product number: 007448
Product name: Lefamulin(BC-3781)
Packaging: 004
Price: $450
Updated: 2021/12/16

DC Chemicals

Product number: DC8172
Product name: Lefamulin(BC-3781)
Purity: >98%
Packaging: 100mg
Price: $1000
Updated: 2021/12/16

DC Chemicals

Product number: DC8172
Product name: Lefamulin(BC-3781)
Purity: >98%
Packaging: 250mg
Price: $1700
Updated: 2021/12/16

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Lefamulin Chemical Properties,Usage,Production

Uses

Lefamulin is an antibiotic medication used in the treatment of adults with community-acquired bacterial pneumonia.

Biological Activity

Lefamulin inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. Specifically, it binds to the peptidyl transferase center of the ribosome and inhibits the transfer of amino acids to growing polypeptide chains, which leads to the inhibition of bacterial protein synthesis and bacterial death. Lefamulin is active against a wide range of Gram-positive bacteria, including Streptococcus pneumoniae, Staphylococcus aureus, and methicillin-resistant S. aureus (MRSA), as well as some atypical bacteria such as Legionella species. It has also been shown to have activity against some Gram-negative bacteria, including Haemophilus influenzae and Moraxella catarrhalis.

Lefamulin Preparation Products And Raw materials

Raw materials

Preparation Products

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Lefamulin Suppliers

China 59 India 1 United States 3 Global 63

BEIJING INNO-TECH PHARMIC TECHNOLOGY CO.,LTD

Tel: 15011485209
Country: China
ProdList: 145
Advantage: 58

ZhengZhou Yimi Pharma R&D Co.,LTD.

Tel: 15393710992
Email: 375000787@QQ.com
Country: China
ProdList: 21
Advantage: 58

Bayee Biotech (Anqing) Co., Ltd.

Tel: 0556-5032306 18917961636
Fax: +86-556-5032307
Email: wtx@bayeebio.com
Country: China
ProdList: 264
Advantage: 61

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18097
Advantage: 56

Chengdu Miracle Pharmaceutical Co., Ltd.

Tel: 028-86136736 19130631884
Fax: 028-85265615
Email: sales@mic-pharma.com
Country: China
ProdList: 278
Advantage: 56

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9805
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2951
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7312
Advantage: 58

Chengdu Apis Pharmaceutical Technology Co.,Ltd

Tel: 13568817957
Fax: 028-66535130
Email: dudes@163.com
Country: China
ProdList: 299
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View Lastest Price from Lefamulin manufacturers

Zhengzhou Anbu Chem Co.,Ltd

Product: Lefamulin 1061337-51-6
Price: US $0.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2023-06-13

1061337-51-6, LefamulinRelated Search:

Lefamulin

2-[[(1R,2R,4R)-4-Amino-2-hydroxycyclohexyl]thio]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester

BC 3781

Lefamulin(BC-3781)

Acetic acid, 2-[[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate

Lefamulin, 10 mM in DMSO

1061337-51-6

C28H45NO5S

API