GDC-0810(ARN-810)

ChemicalBook > CAS DataBase List > GDC-0810(ARN-810)

Product Name: GDC-0810(ARN-810)
CAS No.: 1365888-06-7
Chemical Name: GDC-0810(ARN-810)
Synonyms: RG6046;RG 6046;ARN-810;CS-2080;RG-6046;GDC-0810;Brilanestrant);GDC-0810(ARN-810);ARN-810;BRILANESTRANT;GDC-0810 (Brilanestrant)
CBNumber: CB93040499
Molecular Formula: C26H20ClFN2O2
Formula Weight: 446.9
MOL File: 1365888-06-7.mol

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GDC-0810(ARN-810) Property

Boiling point:: 622.8±55.0 °C(Predicted)
Density: 1.342±0.06 g/cm3(Predicted)
solubility: DMSO:89.0(Max Conc. mg/mL);199.15(Max Conc. mM)
Ethanol:89.0(Max Conc. mg/mL);199.15(Max Conc. mM)
form: A solid
pka: 13.94±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29595
Product name: ARN810
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 29595
Product name: ARN810
Packaging: 25mg
Price: $510
Updated: 2024/03/01

Cayman Chemical

Product number: 29595
Product name: ARN810
Packaging: 1mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 29595
Product name: ARN810
Packaging: 10mg
Price: $223
Updated: 2024/03/01

TRC

Product number: B677393
Product name: Brilanestrant
Packaging: 10mg
Price: $210
Updated: 2021/12/16

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GDC-0810(ARN-810) Chemical Properties,Usage,Production

Uses

Brilanestrant is an orally bioavailable Selective Estrogen Receptor Degrader (SERD) that demonstrates robust activity in tamoxifen-resistant breast cancer xenografts. GDC-0810 functions by binding to the estrogen receptor, inducing a conformational change resulting in the degradation of the receptor. GDC-0810 or ARN-810 demonstrates robust activity in models of tamoxifen-sensitive and tamoxifen-resistant breast cancer, and is currently in clinical trials in women with locally advanced or metastatic estrogen receptor-positive breast cancer.

GDC-0810(ARN-810) Preparation Products And Raw materials

Raw materials

Preparation Products

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1365888-06-7, GDC-0810(ARN-810)Related Search:

ESTETROL Ethylamine (-)-Varitriol

(E)-3-(4-((E)-2-(2-CHLORO-4-FLUOROPHENYL)-1-(1H-INDAZOL-5-YL)BUT-1-EN-1-YL)PHENYL)ACRYLIC ACID

GDC-0810 (Brilanestrant)

GDC-0810(ARN-810)

GDC-0810

(E)-3-[4-[(E)-2-(2-Chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl]phenyl]-2-propenoic acid

ARN-810

ARN-810;BRILANESTRANT

CS-2080

Brilanestrant)

GDC0810; GDC 0810; GDC-0810; ARN810; ARN 810; ARN-810; RG6046; RG-6046; RG 6046; BRILANESTRANT

RG 6046

RG6046

RG-6046

Brilanestrant (GDC-0810, ARN-810)

2-Propenoic acid, 3-[4-[(1E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)-1-buten-1-yl]phenyl]-, (2E)-

ARN810,inhibit,Estrogen Receptor/ERR,ARN 810,Brilanestrant,Inhibitor

Brilanestrant (GDC-0810)

1365888-06-7

C26H20ClFN2O2