1-(5-BROMO-2-FURYL)ETHANONE
- Product Name
- 1-(5-BROMO-2-FURYL)ETHANONE
- CAS No.
- 3199-50-6
- Chemical Name
- 1-(5-BROMO-2-FURYL)ETHANONE
- Synonyms
- 1-(5-BROMOFURAN-2-YL)ETHANONE;2-ACETYL-5-BROMOFURAN;2-Bromo-5-acetylfuran;1-(5-BROMO-2-FURYL)ETHANONE;Methyl 5-bromo-2-furyl ketone;5-Bromo-2-furyl methyl ketone;Ethanone,1-(5-bromo-2-furanyl)-;1-(5-Bromofuran-2-yl)ethan-1-one;1-(5-Bromofuran-2-yl)ethan-1-one - [B93510]
- CBNumber
- CB9304710
- Molecular Formula
- C6H5BrO2
- Formula Weight
- 189.01
- MOL File
- 3199-50-6.mol
1-(5-BROMO-2-FURYL)ETHANONE Property
- Melting point:
- 96℃
- Boiling point:
- 73-75℃ (4 Torr)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C6H5BrO2/c1-4(8)5-2-3-6(7)9-5/h2-3H,1H3
- InChIKey
- CASNGOWLOZSVMA-UHFFFAOYSA-N
- SMILES
- C(=O)(C1=CC=C(Br)O1)C
Safety
- HS Code
- 2932990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B446345
- Product name
- 1-(5-bromofuran-2-yl)ethanone
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FB139729
- Product name
- 1-(5-Bromofuran-2-yl)ethanone
- Packaging
- 500mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- FB139729
- Product name
- 1-(5-Bromofuran-2-yl)ethanone
- Packaging
- 1g
- Price
- $248
- Updated
- 2021/12/16
- Product number
- FB139729
- Product name
- 1-(5-Bromofuran-2-yl)ethanone
- Packaging
- 2g
- Price
- $431
- Updated
- 2021/12/16
- Product number
- 2H17-9-30
- Product name
- 1-(5-Bromofuran-2-yl)ethanone
- Packaging
- 1g
- Price
- $664
- Updated
- 2021/12/16
1-(5-BROMO-2-FURYL)ETHANONE Chemical Properties,Usage,Production
Synthesis
1192-62-7
3199-50-6
General procedure for the synthesis of 1-(5-bromofuran-2-yl)ethanone using 2-acetylfuran as starting material: under stirring conditions, N-bromosuccinimide (22 mmol) was added batchwise to a solution of 2-acetylfuran (20 mmol) in DMF (20 mL). The reaction mixture was stirred at room temperature overnight before it was poured into cold water to terminate the reaction. Subsequently, the product was extracted with ether (200 mL in three portions). Upon treatment, the target compound 1-(5-bromofuran-2-yl)ethanone was obtained in 61% yield and with a melting point of 92-93 °C (melting point of 94-95 °C after recrystallization from hexane/ethyl ether; for literature values see Gilman H., et al., J. Am. Chem. Soc., 53, 4192-4196 (1931)). The nuclear magnetic resonance hydrogen spectrum (1H NMR, CDCl3) data for the product were as follows: δ 2.45 (s, 3H), 6.49 (d, J = 3.9 Hz, 1H), 7.12 (d, J = 3.6 Hz, 1H). The nuclear magnetic resonance carbon spectrum (13C NMR) data are as follows: δ 185.4, 154.4, 128.2, 118.9, 114.3, 25.7.
References
[1] Journal of Natural Products, 2017, vol. 80, # 9, p. 2561 - 2565
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 14, p. 3658 - 3664
[3] Patent: US2005/282853, 2005, A1. Location in patent: Page/Page column 15; 19
[4] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 7, p. 1784 - 1788
[5] Organic Letters, 2017, vol. 19, # 21, p. 5976 - 5979
1-(5-BROMO-2-FURYL)ETHANONE Preparation Products And Raw materials
Raw materials
Preparation Products
1-(5-BROMO-2-FURYL)ETHANONE Suppliers
- Tel
- --
- Fax
- --
- contact@achemica.com
- Country
- Switzerland
- ProdList
- 6155
- Advantage
- 50
View Lastest Price from 1-(5-BROMO-2-FURYL)ETHANONE manufacturers
- Product
- 1-(5-BROMO-2-FURYL)ETHANONE 3199-50-6
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-09