ChemicalBook > CAS DataBase List > TP-3654

TP-3654

Product Name
TP-3654
CAS No.
1361951-15-6
Chemical Name
TP-3654
Synonyms
TP3654;CS-2702;TP-3654;Nuvisertib;TP-3654 ,S6774;TP3654 ;TP 3654;TP-3654, 10 mM in DMSO;TP3654,inhibit,Pim,TP 3654,Pim kinases,Inhibitor,TP-3654;2-(trans-4-((3-(3-(Trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexyl)propan-2-ol;Cyclohexanemethanol, α,α-dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]-, trans-
CBNumber
CB93049508
Molecular Formula
C22H25F3N4O
Formula Weight
418.46
MOL File
1361951-15-6.mol
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TP-3654 Property

storage temp. 
Store at -20°C
solubility 
DMSO:86.0(Max Conc. mg/mL);200.74(Max Conc. mM)
Ethanol:6.0(Max Conc. mg/mL);14.34(Max Conc. mM)
form 
A crystalline solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29571
Product name
TP-3654
Packaging
5mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
29571
Product name
TP-3654
Packaging
10mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
29571
Product name
TP-3654
Packaging
25mg
Price
$220
Updated
2024/03/01
TRC
Product number
T700558
Product name
TP-3654
Packaging
25mg
Price
$415
Updated
2021/12/16
ChemScene
Product number
CS-6293
Product name
TP-3654
Purity
99.87%
Packaging
100mg
Price
$450
Updated
2021/12/16
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TP-3654 Chemical Properties,Usage,Production

Uses

TP-3654 is a second-generation PIM inhibitor, displaying submicromolar activity in pharmacodynamic biomarker modulation, cell proliferation studies, and colony formation assays.

in vivo

Oral dosing of 200 mg/kg TP-3654 significantly reduces both UM-UC-3 and PC-3 tumor growth measured by volume (caliper) and by final tumor weight, with no significant changes in body weight or gross adverse toxicity[1].

TP-3654 Preparation Products And Raw materials

Raw materials

Preparation Products

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TP-3654 Suppliers

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 18971495150;
Email
sales@sun-shinechem.com
Country
China
ProdList
1077
Advantage
64
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4769
Advantage
55
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
984
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29760
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9757
Advantage
58

1361951-15-6, TP-3654Related Search:


  • TP3654
  • TP-3654
  • CS-2702
  • TP3654 ;TP 3654
  • Cyclohexanemethanol, α,α-dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]-, trans-
  • TP3654,inhibit,Pim,TP 3654,Pim kinases,Inhibitor,TP-3654
  • 2-(trans-4-((3-(3-(Trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexyl)propan-2-ol
  • TP-3654, 10 mM in DMSO
  • TP-3654 ,S6774
  • Nuvisertib
  • 1361951-15-6
  • API