ChemicalBook > CAS DataBase List > 1-(2-Amino-5-hydroxyphenyl)propan-1-one

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Product Name
1-(2-Amino-5-hydroxyphenyl)propan-1-one
CAS No.
35364-15-9
Chemical Name
1-(2-Amino-5-hydroxyphenyl)propan-1-one
Synonyms
aminoketone;2-Amino-5-Hydroxy propiophenone;2'-amino-5'-hydroxypropiophenone;1-(2-Amino-5-hydroxyphenyl)-1-propanone;1-propanone,1-(2-amino-5-hydroxyhenyl)-;1-(2-Amino-5-hydroxyphenyl)propan-1-one;1-Propanone, 1-(2-amino-5-hydroxyphenyl)-
CBNumber
CB93070610
Molecular Formula
C9H11NO2
Formula Weight
165.19
MOL File
35364-15-9.mol
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1-(2-Amino-5-hydroxyphenyl)propan-1-one Property

Melting point:
144.5-144.9 °C
Boiling point:
363.9±32.0 °C(Predicted)
Density 
1.195±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.35±0.18(Predicted)
color 
Light Yellow to Brown
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A611480
Product name
1-(2-Amino-5-hydroxyphenyl)propan-1-one
Packaging
2.5g
Price
$1295
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0291115
Product name
2-AMINO-5-HYDROXYPROPIOPHENONE
Purity
95.00%
Packaging
5G
Price
$1443.75
Updated
2021/12/16
Matrix Scientific
Product number
178544
Product name
1-(2-Amino-5-hydroxyphenyl)propan-1-one
Packaging
1g
Price
$1486
Updated
2021/12/16
AK Scientific
Product number
5920CS
Product name
1-(2-Amino-5-hydroxyphenyl)propan-1-one
Packaging
25mg
Price
$252
Updated
2021/12/16
AK Scientific
Product number
5920CS
Product name
1-(2-Amino-5-hydroxyphenyl)propan-1-one
Packaging
250mg
Price
$455
Updated
2021/12/16
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1-(2-Amino-5-hydroxyphenyl)propan-1-one Chemical Properties,Usage,Production

Uses

1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-?ring-?modified (RS)?-?camptothecin analogs as antitumor agents.

Preparation

Obtained by UV-irradiation of 3-ethyl-2,1-benzisoxazole in 66% sulfuric acid for 90 min at 80–90°
Also prepared from 2-nitro-5-hydroxybenzaldehyde (five steps) or from p-anisidine.

1-(2-Amino-5-hydroxyphenyl)propan-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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35364-15-9, 1-(2-Amino-5-hydroxyphenyl)propan-1-oneRelated Search:


  • 1-(2-Amino-5-hydroxyphenyl)propan-1-one
  • 1-propanone,1-(2-amino-5-hydroxyhenyl)-
  • 2-Amino-5-Hydroxy propiophenone
  • 1-Propanone, 1-(2-amino-5-hydroxyphenyl)-
  • aminoketone
  • 1-(2-Amino-5-hydroxyphenyl)-1-propanone
  • 2'-amino-5'-hydroxypropiophenone
  • 35364-15-9