ChemicalBook > CAS DataBase List > 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate

4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate

Product Name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate
CAS No.
202189-76-2
Chemical Name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate
Synonyms
Bilastine ITS-1;*Mesna Impurity 16;Bilastine impurity C;Bilastine Impurity 03;Bilastine ITS-1，Bilastine intermediate;2-[4-[1-(4,4-Dimethyl-5H-Oxazol-2-Yl)-1- Methyl-Ethyl]Phenyl;4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate;2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1-methyl-ethyl]phenyl]ethyl 4-methylbenzenesulfonate;4-(2-((4,4-dimethyl-4,5-dihydroxyoxazol-2-yl)propan-2yl)phenethyl-4-methylbenzenesulfonate;4 - (2 - (4,4-dimethyl-4,5-dihydroxazol-2-yl) propyl-2-yl) phenylethyl 4-methylbenzene sulfonate
CBNumber
CB93076733
Molecular Formula
C23H29NO4S
Formula Weight
415.55
MOL File
202189-76-2.mol
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4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Property

Boiling point:
545.1±45.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
solubility 
soluble in Dichloromethane;
pka
5.78±0.70(Predicted)
Water Solubility 
5.717μg/L at 25℃
InChI
InChI=1S/C23H29NO4S/c1-17-6-12-20(13-7-17)29(25,26)28-15-14-18-8-10-19(11-9-18)23(4,5)21-24-22(2,3)16-27-21/h6-13H,14-16H2,1-5H3
InChIKey
BGUOPDZOVDIWLE-UHFFFAOYSA-N
SMILES
C(C1C=CC(CCOS(C2C=CC(C)=CC=2)(=O)=O)=CC=1)(C1OCC(C)(C)N=1)(C)C
LogP
6.6
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
8683BB
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Packaging
5g
Price
$165
Updated
2021/12/16
Ambeed
Product number
A176690
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Purity
97%
Packaging
250mg
Price
$10
Updated
2021/12/16
Ambeed
Product number
A176690
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Purity
97%
Packaging
5g
Price
$78
Updated
2021/12/16
Alichem
Product number
202189762
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Packaging
5g
Price
$176
Updated
2021/12/16
Crysdot
Product number
CD11169316
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Purity
97%
Packaging
10g
Price
$257
Updated
2021/12/16
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4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Chemical Properties,Usage,Production

Uses

4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate (or Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester)) is an intermediate used in the synthesis of Bilastine-d6 (B385002), which is labelled Bilastine. It is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.

4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Suppliers

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View Lastest Price from 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate manufacturers

Anhui Dexinjia Biopharm Co., Ltd
Product
Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester) 202189-76-2
Price
US $500.00-8000.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg per month
Release date
2023-03-23
Shanghai Joiny Pharmaceutical Co.,LTD
Product
2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1 methyl-ethyl] phenyl]ethyl 4-methylbenzenesulfonate 202189-76-2
Price
US $0.00/kg
Min. Order
1kg
Purity
96%
Supply Ability
200kg
Release date
2022-12-13
Career Henan Chemical Co
Product
Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester) 202189-76-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-09

202189-76-2, 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonateRelated Search:

2-(2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole 2-Propenoic acid, 3-[3-[(phenylaMino)sulfonyl]phenyl]-, Methyl ester, (2E)- Bilastine 4-FORMYLCINNAMIC ACID METHYL ESTER 2-Propenoic acid, 3-[3-[(phenylaMino)sulfonyl]phenyl]-, ethyl ester, (2E)- 2-(1-(4-(2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)propan- 2-yl)phenethyl)piperidin-4-yl)-1H-benzo[d]imidazole 4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL

  • Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester)
  • 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate
  • 2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1-methyl-ethyl]phenyl]ethyl 4-methylbenzenesulfonate
  • Bilastine impurity C
  • 2-[4-[1-(4,4-Dimethyl-5H-Oxazol-2-Yl)-1- Methyl-Ethyl]Phenyl
  • Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 1-(4-methylbenzenesulfonate)
  • 4 - (2 - (4,4-dimethyl-4,5-dihydroxazol-2-yl) propyl-2-yl) phenylethyl 4-methylbenzene sulfonate
  • 4-(2-((4,4-dimethyl-4,5-dihydroxyoxazol-2-yl)propan-2yl)phenethyl-4-methylbenzenesulfonate
  • 2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl 4-methylbenzene-1-sulfonate
  • Bilastine ITS-1
  • Bilastine ITS-1，Bilastine intermediate
  • 2-(4-(2-(4-(1-(2-hydroxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoic acid hydrochloride
  • 2-(4-[1-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-1-methyl-ethyl]-phenyl)-ethyl toluene-4-sulfonate
  • *Mesna Impurity 16
  • Bilastine Impurity 03
  • 202189-76-2