4-AMINO-3,5-DIMETHYL-BENZONITRILE

Product Name: 4-AMINO-3,5-DIMETHYL-BENZONITRILE
CAS No.: 74896-24-5
Chemical Name: 4-AMINO-3,5-DIMETHYL-BENZONITRILE
Synonyms: NSC 128902;4-Amino-3,5-dimethylbenzo...;4-AMINO-3,5-DIMETHYL-BENZONITRILE;Benzonitrile, 4-amino-3,5-dimethyl-;4-Amino-3,5-dimethyl-benzonitrile, CAS 74896-24-5
CBNumber: CB9311646
Molecular Formula: C9H10N2
Formula Weight: 146.19
MOL File: 74896-24-5.mol

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4-AMINO-3,5-DIMETHYL-BENZONITRILE Property

Melting point:: 106.0-107.5 °C
Boiling point:: 322.2±30.0 °C(Predicted)
Density: 1.07±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 1.43±0.10(Predicted)
Appearance: Brown to gray Solid

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 26-36/37/39
RIDADR: 3439
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-M3145
Product name: NSC128902
Purity: 99.96%
Packaging: 10g
Price: $56
Updated: 2021/12/16

AK Scientific

Product number: W8246
Product name: 4-Amino-3,5-dimethylbenzonitrile
Packaging: 1g
Price: $67
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA142959
Product name: 4-amino-3,5-dimethyl-benzonitrile
Packaging: 500mg
Price: $85
Updated: 2021/12/16

ChemScene

Product number: CS-M3145
Product name: NSC128902
Purity: 99.96%
Packaging: 25g
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA142959
Product name: 4-amino-3,5-dimethyl-benzonitrile
Packaging: 1g
Price: $151
Updated: 2021/12/16

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4-AMINO-3,5-DIMETHYL-BENZONITRILE Chemical Properties,Usage,Production

Synthesis

24596-19-8

544-92-3

74896-24-5

GENERAL STEPS: A mixture of 4-bromo-2,6-dimethylaniline (1.90 g, 9.50 mmol) and cuprous(I) cyanide (1.71 g, 19.1 mmol) in N-methylpyrrolidone (NMP, 25 mL) was reacted with stirring at 160 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature. Subsequently, water (10 mL) and ammonium hydroxide solution (10 mL) were added to the reaction mixture and extracted with ethyl acetate (3 × 50 mL) to separate the products. The organic phases were combined, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The crude product was purified by fast column chromatography (dichloromethane as eluent) to afford 4-amino-3,5-dimethylbenzonitrile 1.19 g (86% yield, 1.39 g theoretical yield). The product was analyzed by LCMS (Method B) with a retention time (RT) of 1.925 min and a molecular ion peak (MH+) of 147. 1H NMR (500 MHz, CDCl3) δ 7.22 (s, 2H), 2.18 (s, 6H).

References

[1] Patent: US2006/287287, 2006, A1. Location in patent: Page/Page column 34
[2] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 9, p. 3115 - 3126
[3] Journal of Heterocyclic Chemistry, 1997, vol. 34, # 1, p. 269 - 272
[4] Patent: US2008/146595, 2008, A1. Location in patent: Page/Page column 29; 30
[5] Patent: WO2006/79656, 2006, A1. Location in patent: Page/Page column 20

4-AMINO-3,5-DIMETHYL-BENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMINO-3,5-DIMETHYL-BENZONITRILE Suppliers

China 66 Germany 1 India 3 The Netherlands 1 United Kingdom 2 United States 14 Global 87

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View Lastest Price from 4-AMINO-3,5-DIMETHYL-BENZONITRILE manufacturers

Career Henan Chemical Co

Product: 4-AMINO-3,5-DIMETHYL-BENZONITRILE 74896-24-5
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-14

74896-24-5, 4-AMINO-3,5-DIMETHYL-BENZONITRILERelated Search:

2-AMINO-3,5-DIMETHYL-BENZONITRILE 4-AMINO-3,5-DIMETHYL-BENZONITRILE N-(2,4-DICYANO-6-METHYLPHENYL)ACETAMIDE 3,5-BIS(TRIFLUOROMETHYL)-4-AMINOBENZONITRILE

4-Amino-3,5-dimethylbenzo...

NSC 128902

4-AMINO-3,5-DIMETHYL-BENZONITRILE

Benzonitrile, 4-amino-3,5-dimethyl-

4-Amino-3,5-dimethyl-benzonitrile, CAS 74896-24-5

74896-24-5