RS 102221 HYDROCHLORIDE

Product Name: RS 102221 HYDROCHLORIDE
CAS No.: 185376-97-0
Chemical Name: RS 102221 HYDROCHLORIDE
Synonyms: RS 102221;RS102221HCl;RS 102221 hydrochlor;RS 102221 HYDROCHLORIDE;4-dione hydrochloride hydrate;RS-102221 hydrochloride hydrate;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dionehy;N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
CBNumber: CB9312416
Molecular Formula: C27H31F3N4O7S
Formula Weight: 612.62
MOL File: 185376-97-0.mol

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RS 102221 HYDROCHLORIDE Property

Density: 1.45
storage temp.: Store at RT
solubility: DMSO: ≥20mg/mL
form: powder
color: white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 1050
Product name: RS102221hydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $195
Updated: 2021/12/16

Tocris

Product number: 1050
Product name: RS102221hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $818
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0006966
Product name: RS-102221
Purity: 95.00%
Packaging: 50MG
Price: $1230.95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0006966
Product name: RS-102221
Purity: 95.00%
Packaging: 10MG
Price: $709.46
Updated: 2021/12/16

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RS 102221 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

RS 102221 Hydrochloride is a selective 5-HT2C receptor antagonist.

Definition

ChEBI: N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide is an aromatic ketone.

Biological Activity

Potent and selective 5-HT 2C antagonist (pK i = 8.7). Displays ~ 100-fold selectivity over the 5-HT 2A and 5-HT 2B subtypes and is > 100-fold selective over other 5-HT receptors, a- and b-adrenergic and muscarinic ACh receptors.

RS 102221 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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RS 102221 HYDROCHLORIDE Suppliers

China 8 Europe 1 Germany 1 Japan 1 United Kingdom 2 United States 1 Global 14

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4963
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28806
Advantage: 58

Jinan ponder chemical co. LTD

Tel: 0531-0000
Email: thinklifescience@163.com
Country: China
ProdList: 19689
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 13774214275
Email: zhouzz@univ-bio.com
Country: China
ProdList: 24994
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

Tel: 13915962545
Email: 2881759498@qq.com
Country: China
ProdList: 3660
Advantage: 58

185376-97-0, RS 102221 HYDROCHLORIDERelated Search:

RS 102221 HYDROCHLORIDE 1,3,8-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE 5-METHANESULPHONAMIDO-2-HYDROXYACETOPHENONE N-(5-ACETYL-2-HYDROXY-PHENYL)-METHANESULFONAMIDE

RS 102221 HYDROCHLORIDE

8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dionehy

RS102221HCl

8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.

8-[5-(2,4-Dimethoxy-5-(4-Trifluoromethylphenylsulphonamido)Phenyl-5-Oxopentyl)]-1,3,8-Triazaspiro[4.5]Decane-2,4-Dione Hydrochloride

8-[5-(2,4-DIMETHOXY-5-(4-TRIFLUOROMETHYLPHENYLSULPHONAMIDO)PHENYL-5-OXOPENTYL)]-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE HYDROCHLORIDE

N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide

RS 102221

4-dione hydrochloride hydrate

8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2

RS-102221 hydrochloride hydrate

Benzenesulfonamide, N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-

RS 102221 hydrochlor

185376-97-0

C27H31F3N4O7S

C27H32ClF3N4O7S

C27H31F3N4O7SHCl