ARS-853

Product Name: ARS-853
CAS No.: 1629268-00-3
Chemical Name: ARS-853
Synonyms: ARS-853;CS-2646;ARS-853 (ARS853);ARS-853, 10 mM in DMSO;1-(3-(4-((4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl)glycyl)piperazin-1-yl)azetidin-1-yl)prop-2-en-1-one;ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,covalent,ARS853,G12C;2-Propen-1-one, 1-[3-[4-[2-[[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl]amino]acetyl]-1-piperazinyl]-1-azetidinyl]-
CBNumber: CB93133108
Molecular Formula: C22H29ClN4O3
Formula Weight: 432.94
MOL File: 1629268-00-3.mol

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ARS-853 Property

Boiling point:: 691.6±55.0 °C(Predicted)
Density: 1.357±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 50 mg/ml
form: A crystalline solid
pka: 9.47±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19137
Product name: ARS853
Purity: ≥95%
Packaging: 500μg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 19137
Product name: ARS853
Purity: ≥95%
Packaging: 1mg
Price: $230
Updated: 2024/03/01

Cayman Chemical

Product number: 19137
Product name: ARS853
Purity: ≥95%
Packaging: 5mg
Price: $601
Updated: 2024/03/01

Cayman Chemical

Product number: 19137
Product name: ARS853
Purity: ≥95%
Packaging: 10mg
Price: $841
Updated: 2024/03/01

TRC

Product number: A774050
Product name: ARS-853
Packaging: 10mg
Price: $2890
Updated: 2021/12/16

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ARS-853 Chemical Properties,Usage,Production

Uses

ARS-853 is an allele-specific inhibitor that inhibits KRASG12C signaling and cancer cell growth.

IC 50

KRAS(G12C): 2.5 μM (IC₅₀)

ARS-853 Preparation Products And Raw materials

Raw materials

Preparation Products

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ARS-853 Suppliers

China 68 India 1 United States 10 Global 79

BOC Sciences

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Dalian Meilun Biotech Co., Ltd.

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MedChemexpress LLC

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ShangHai Caerulum Pharma Discovery Co., Ltd.

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Bide Pharmatech Ltd.

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Changzhou Renaissance Chem Co. Ltd

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Shanghai Lollane Biological Technology Co.,Ltd.

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Shanghai Synchem Pharma Co., ltd

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Shanghai YuanYe Biotechnology Co., Ltd.

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Beijing Solarbio Science & Tecnology Co., Ltd.

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1629268-00-3, ARS-853Related Search:

ARS-853

ARS-853 (ARS853)

CS-2646

2-Propen-1-one, 1-[3-[4-[2-[[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl]amino]acetyl]-1-piperazinyl]-1-azetidinyl]-

1-(3-(4-((4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl)glycyl)piperazin-1-yl)azetidin-1-yl)prop-2-en-1-one

ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,covalent,ARS853,G12C

ARS-853, 10 mM in DMSO

1629268-00-3