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Fingolimod Impurity 8

Product Name
Fingolimod Impurity 8
CAS No.
162358-96-5
Chemical Name
Fingolimod Impurity 8
Synonyms
Fingolimod Impurity 7;2-octylphenethyl iodide;Benzene, 1-(2-iodoethyl)-2-octyl-;1-?(2-?Iodoethyl)?-?2-?octylbenzene
CBNumber
CB93133911
Molecular Formula
C16H25I
Formula Weight
344.27
MOL File
162358-96-5.mol
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Fingolimod Impurity 8 Property

Boiling point:
363.2±21.0 °C(Predicted)
Density 
1.261±0.06 g/cm3(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
I706320
Product name
1-​(2-​Iodoethyl)​-​2-​octylbenzene
Packaging
5mg
Price
$745
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0045936
Product name
FINGOLIMOD IMPURITY 2
Purity
95.00%
Packaging
5MG
Price
$451.77
Updated
2021/12/16
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Fingolimod Impurity 8 Chemical Properties,Usage,Production

Uses

1-?(2-?Iodoethyl)?-?2-?octylbenzene is an impurity of Fingloimod (F805000), also known as FTY720. FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).

Fingolimod Impurity 8 Preparation Products And Raw materials

Raw materials

Preparation Products

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