ChemicalBook > CAS DataBase List > (1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate
(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate
- Product Name
- (1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate
- CAS No.
- 419563-23-8
- Chemical Name
- (1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate
- Synonyms
- Peramivir Intermediater 2;(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate;Methyl (1R,4S)-4-Amino-2-cyclopentenecarboxylate (2S,3S)-2,3-Dihydroxysuccinate;(2S,3S)-2,3-Dihydroxybutanedioic acid methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate;Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid
- CBNumber
- CB93137449
- Molecular Formula
- C11H17NO8
- Formula Weight
- 291.26
- MOL File
- 419563-23-8.mol
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N-Bromosuccinimide Price
TRC
- Product number
- M220435
- Product name
- Methyl(1R,4S)-4-Amino-2-cyclopentene-1-carboxylate(2S,3S)-2,3-DihydroxybutanedioicAcid
- Packaging
- 10g
- Price
- $650
- Updated
- 2021/12/16
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(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Chemical Properties,Usage,Production
Uses
Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Preparation Products And Raw materials
Raw materials
Preparation Products
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