Aramchol
- Product Name
- Aramchol
- CAS No.
- 246529-22-6
- Chemical Name
- Aramchol
- Synonyms
- Aramchol;C20-FABAC;Icomidocholic acid;Aramchol (C20-FABAC);Aramchol (in progress);Aramchol, 10 mM in DMSO;Inhibitor,inhibit,Aramchol;Icomidocholic acid (Aramchol);Arachidyl amido cholanoic acid;(3beta)-Arachidylamido-7alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
- CBNumber
- CB93146809
- Molecular Formula
- C44H79NO5
- Formula Weight
- 702.1
- MOL File
- 246529-22-6.mol
Aramchol Property
- Melting point:
- 109-113°C
- Boiling point:
- 806.0±65.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.76±0.10(Predicted)
- form
- Solid
- color
- White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML2352
- Product name
- Aramchol
- Purity
- ≥98% (HPLC)
- Packaging
- 5 mg
- Price
- $99.54
- Updated
- 2025/07/31
- Product number
- SML2352
- Product name
- Aramchol
- Purity
- ≥98% (HPLC)
- Packaging
- 25 mg
- Price
- $296.1
- Updated
- 2025/07/31
- Product number
- 22478
- Product name
- Aramchol
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $40
- Updated
- 2024/03/01
- Product number
- 22478
- Product name
- Aramchol
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $99
- Updated
- 2024/03/01
- Product number
- 22478
- Product name
- Aramchol
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $178
- Updated
- 2024/03/01
Aramchol Chemical Properties,Usage,Production
Uses
Aramchol is a fatty acid conjugate that exhibits?hypocholesterolemic effects. Studies have shown that aramchol?suppresses the activity of?stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.
Biological Activity
Arachidyl amido cholanoic acid (Aramchol) is a cholesterol solubilizer th at has the potential to prevent and dissolves cholesterol gallstones in inbred mice and in human gallbladder bile ex vivo.', 'Aramchol is a bile salt fatty acid conjugate (BAFAC) of arachidic acid and cholic acid. It has been shown to reduce liver f at by a dual mechanism of action. It inhibits the activity of liver stearoyl coenzyme A desaturase 1 (SCD1), decreasing the synthesis of fatty acids. In addition, it activates cholesterol efflux by stimulating the adenosine triphosphate–binding cassette transporter A1 (ABCA1). Aramchol has been investigated for treatment for nonalcoholic steatohepatitis, or NASH.
Aramchol Preparation Products And Raw materials
Raw materials
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