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Biliverdin (hydrochloride)

Product Name
Biliverdin (hydrochloride)
CAS No.
856699-18-8
Chemical Name
Biliverdin (hydrochloride)
Synonyms
3-((Z)-2-((3-(2-Carboxyethyl)-4-methyl-5-((Z)-(3-methyl-5-oxo-4-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-1H-pyrrol-2-yl)methylene)-4-methyl-5-((Z)-(4-methyl-5-oxo-3-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-2H-pyrrol-3-yl)propanoic acid hydrochloride
CBNumber
CB93152561
Molecular Formula
C33H35ClN4O6
Formula Weight
619.12
MOL File
856699-18-8.mol
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Biliverdin (hydrochloride) Property

storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml
form 
A crystalline solid
color 
Green to dark green
InChIKey
SRFCAIVUFIHMAV-FOAUCVKNSA-N
SMILES
C(/C1NC(/C=C2\NC(=O)C(C=C)=C\2C)=C(C)C=1CCC(=O)O)=C1/N=C(C=C2NC(=O)C(C)=C2C=C)C(C)=C/1CCC(=O)O.Cl |c:27|
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
30891
Product name
Biliverdin hydrochloride
Purity
≥97.0% (TLC)
Packaging
10 mg
Price
$41.8
Updated
2025/07/31
Sigma-Aldrich
Product number
30891
Product name
Biliverdin hydrochloride
Purity
≥97.0% (TLC)
Packaging
50 mg
Price
$153
Updated
2025/07/31
Cayman Chemical
Product number
19257
Product name
Biliverdin (hydrochloride)
Purity
≥98% mixture of isomers
Packaging
10mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
19257
Product name
Biliverdin (hydrochloride)
Purity
≥98% mixture of isomers
Packaging
50mg
Price
$123
Updated
2024/03/01
Cayman Chemical
Product number
19257
Product name
Biliverdin (hydrochloride)
Purity
≥98% mixture of isomers
Packaging
100mg
Price
$213
Updated
2024/03/01
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Biliverdin (hydrochloride) Chemical Properties,Usage,Production

Description

Biliverdin is a green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and is further reduced to bilirubin by biliverdin reductase.1,2 Biliverdin regulates the cellular heme degradation process by inhibiting substrates from binding to the catalytic site of heme oxygenase. Bile pigments such as biliverdin are known to possess anti-mutagenic and antioxidant properties.3,4

Uses

Biliverdin hydrochloride, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin hydrochloride is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin hydrochloride is anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant[1].

in vivo

Biliverdin hydrochloride significant decreases the intimal hyperplasia following balloon angioplasty and vascular grafting in rats[1].

IC 50

Human Endogenous Metabolite

References

1. Liu, Y., Mo?nne-Loccoz, P., Loehr, T.M., et al. Heme oxygenase-1, intermediates in verdoheme formation and the requirement for reduction equivalents J. Biol. Chem. 272,6909-6917(1997).
2. Maines, M.D. The heme oxygenase system: A regulator of second messenger gases Annu. Rev. Pharmacol. Toxicol. 37,517-554(1997).
3. Bulmer, A.C., Ried, K., Blanchfield, J.T., et al. The anti-mutagenic properties of bile pigments Mutat. Res. 658(1-2),28-41(2008).
4. M?lzer, C., Huber, H., Steyrer, A., et al. In vitro antioxidant capacity and antigenotoxic properties of protoporphyrin and structurally related tetrapyrroles Free Radic. Res. 46(11),1369-1377(2012).

Biliverdin (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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Biliverdin (hydrochloride) Suppliers

Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

856699-18-8, Biliverdin (hydrochloride)Related Search:


  • 3-((Z)-2-((3-(2-Carboxyethyl)-4-methyl-5-((Z)-(3-methyl-5-oxo-4-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-1H-pyrrol-2-yl)methylene)-4-methyl-5-((Z)-(4-methyl-5-oxo-3-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-2H-pyrrol-3-yl)propanoic acid hydrochloride
  • 856699-18-8