ChemicalBook > CAS DataBase List > GSK106 (hydrochloride)
GSK106 (hydrochloride)
- Product Name
- GSK106 (hydrochloride)
- CAS No.
- 1652591-82-6
- Chemical Name
- GSK106 (hydrochloride)
- Synonyms
- GSK106;GSK106 (hydrochloride);(3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone Hydrochloride
- CBNumber
- CB93152622
- Molecular Formula
- C24H28ClN5O
- Formula Weight
- 437.965
- MOL File
- 1652591-82-6.mol
More
Less
GSK106 (hydrochloride) Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- color
- Off-white to light yellow
More
Less
N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 17490
- Product name
- GSK106 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $37
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17490
- Product name
- GSK106 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17490
- Product name
- GSK106 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $283
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17490
- Product name
- GSK106 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $494
- Updated
- 2024/03/01
TRC
- Product number
- G797390
- Product name
- (3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanoneHydrochloride
- Packaging
- 5mg
- Price
- $235
- Updated
- 2021/12/16
More
Less
GSK106 (hydrochloride) Chemical Properties,Usage,Production
Description
Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline. Citrullination of proteins has normal roles in gene regulation and pathological roles in immunological and inflammatory diseases. GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199 . It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils (IC50s > 100 μM). See the Structural Genomics Consortium (SGC) website for more information on both GSK484 and GSK106.
Uses
(3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone Hydrochloride is structurally similar to (3-Amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone TFA Salt (G797395) and is suitable to use as a control to identify inhibitors for protein arginine deiminase 4 (PAD4).
GSK106 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
GSK106 (hydrochloride) Suppliers
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4566
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9806
- Advantage
- 58
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8012
- Advantage
- 62
- Tel
- 400-9205774
- sales@glpbio.cn
- Country
- China
- ProdList
- 6777
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30239
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9409
- Advantage
- 58
- Tel
- 0519-85788828 13775037613
- sales@chemrenpharm.com
- Country
- China
- ProdList
- 3600
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11218
- Advantage
- 58
- Tel
- 15317229551
- Fax
- QQ:3607245178
- 15151849396@163.com
- Country
- China
- ProdList
- 999
- Advantage
- 58
- Tel
- 15869524721
- 3525679403@qq.com
- Country
- China
- ProdList
- 4009
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44806
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8140
- Advantage
- 58
- Tel
- 0519-85524369
- 3477467573@qq.com
- Country
- China
- ProdList
- 8617
- Advantage
- 58
- Tel
- 15071299552
- Fax
- QQ:262933239
- 262933239@qq.com
- Country
- China
- ProdList
- 6887
- Advantage
- 58
- Tel
- 17722895060 19139748274
- Fax
- QQ：3311217266
- info@kehobio.com
- Country
- China
- ProdList
- 2415
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24644
- Advantage
- 58
- Tel
- 024-024-88590548 18341751992
- 757984502@qq.com
- Country
- China
- ProdList
- 891
- Advantage
- 58
- Tel
- 13720134139 13720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 5821
- Advantage
- 58
- Tel
- 0513-66337626 18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 4988
- Advantage
- 58
- Tel
- 021-54306202 18917919676
- info@hanhongsci.com
- Country
- China
- ProdList
- 29979
- Advantage
- 58
- Tel
- 13298105281 13298105281
- 1522334715@qq.com
- Country
- China
- ProdList
- 7508
- Advantage
- 58
- Tel
- 13823398779 18670069958
- 3062105966@qq.com
- Country
- China
- ProdList
- 3262
- Advantage
- 58
- Tel
- 17316404525
- 209533805@qq.com
- Country
- China
- ProdList
- 9765
- Advantage
- 58
- Tel
- +8613720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 5221
- Advantage
- 58
- Tel
- +86-18341751992 +86-15382112998
- 757984502@qq.com
- Country
- China
- ProdList
- 892
- Advantage
- 58
- Tel
- +8618327326525
- masar@topule.com
- Country
- China
- ProdList
- 8467
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@zzsrm.com
- Country
- CHINA
- ProdList
- 6650
- Advantage
- 58