ChemicalBook > CAS DataBase List > 4-Fluoro-3-hydroxybenzyl alcohol

4-Fluoro-3-hydroxybenzyl alcohol

Product Name
4-Fluoro-3-hydroxybenzyl alcohol
CAS No.
934241-78-8
Chemical Name
4-Fluoro-3-hydroxybenzyl alcohol
Synonyms
2-Fluoro-5-(hydroxymethyl)phenol;4-Fluoro-3-hydroxybenzyl alcohol;Benzenemethanol, 4-fluoro-3-hydroxy-;2-Fluoro-5-(hydroxymethyl)phenol 95+%
CBNumber
CB93154530
Molecular Formula
C7H7FO2
Formula Weight
142.13
MOL File
934241-78-8.mol
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4-Fluoro-3-hydroxybenzyl alcohol Property

Boiling point:
272.4±25.0 °C(Predicted)
Density 
1.342±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
8.49±0.10(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2908190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
296410
Product name
4-Fluoro-3-hydroxybenzyl alcohol
Packaging
1.00g
Price
$121
Updated
2026/05/19
Matrix Scientific
Product number
296410
Product name
4-Fluoro-3-hydroxybenzyl alcohol
Packaging
5.00g
Price
$422
Updated
2026/05/19
Matrix Scientific
Product number
296410
Product name
4-Fluoro-3-hydroxybenzyl alcohol
Packaging
25.00g
Price
$1621
Updated
2026/05/19
Synthonix
Product number
F45920
Product name
4-Fluoro-3-hydroxybenzyl alcohol
Purity
97%
Packaging
250mg
Price
$50
Updated
2026/05/06
Synthonix
Product number
F45920
Product name
4-Fluoro-3-hydroxybenzyl alcohol
Purity
97%
Packaging
1g
Price
$130
Updated
2026/05/06
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4-Fluoro-3-hydroxybenzyl alcohol Chemical Properties,Usage,Production

Synthesis

214822-96-5

934241-78-8

The general procedure for the synthesis of 4-fluoro-3-hydroxybenzyl alcohol from methyl 4-fluoro-3-hydroxybenzoate was as follows: LiBH4 (2.37 g, 109 mmol) was suspended in THF (50 mL) at room temperature, followed by the addition of methyl 4-fluoro-3-hydroxybenzoate (5.0 g, 27.2 mmol). The reaction mixture was stirred under reflux conditions for 24 hours. After completion of the reaction, the mixture was concentrated. The residue was partitioned between EtOAc (100 mL) and 1N HCl (100 mL). The aqueous layer was extracted with EtOAc (50 mL × 2) and the combined organic layers were washed with brine, dried over MgSO4 and concentrated. The residue was purified by fast column chromatography to afford 4-fluoro-3-hydroxybenzyl alcohol (2.76 g, 19.4 mmol, 66% yield) as a white solid.1H NMR (CDCl3) δ: 7.09-7.00 (2H, m), 6.88-6.82 (1H, m), 5.24 (1H, d, J = 4.0 Hz), 4.60 (2H, s) , 1.68 (1H, brs).

References

[1] Patent: US2011/136801, 2011, A1. Location in patent: Page/Page column 64

4-Fluoro-3-hydroxybenzyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Fluoro-3-hydroxybenzyl alcohol Suppliers

Amadis Chemical Company Limited
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0086-571-89925065
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China
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AAB-PHARMA LIMITED
Tel
025-66800956 18800000000
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qq3325708371
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sales@njdmchem.com
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China
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50
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934241-78-8, 4-Fluoro-3-hydroxybenzyl alcoholRelated Search:


  • 4-Fluoro-3-hydroxybenzyl alcohol
  • 2-Fluoro-5-(hydroxymethyl)phenol
  • 2-Fluoro-5-(hydroxymethyl)phenol 95+%
  • Benzenemethanol, 4-fluoro-3-hydroxy-
  • 934241-78-8