N-methyl-N'-(azide-PEG3)-Cy3
- Product Name
- N-methyl-N'-(azide-PEG3)-Cy3
- CAS No.
- 2107273-16-3
- Chemical Name
- N-methyl-N'-(azide-PEG3)-Cy3
- Synonyms
- N-methyl-N'-(azide-PEG3)-Cy3;N-Methyl-N'-(N3-PEG3-CH2CH2)-Cy3
- CBNumber
- CB93163091
- Molecular Formula
- C32H42ClN5O3
- Formula Weight
- 580.17
- MOL File
- 2107273-16-3.mol
N-methyl-N'-(azide-PEG3)-Cy3 Property
- solubility
- Soluble in DMSO, DMF, DCM, low solubility in water
N-Bromosuccinimide Price
- Product number
- BP-23022
- Product name
- N-methyl-N'-(azide-PEG3)-Cy3
- Purity
- 97%
- Packaging
- 1mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- BP-23022
- Product name
- N-methyl-N'-(azide-PEG3)-Cy3
- Purity
- 97%
- Packaging
- 5mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- BP-23022
- Product name
- N-methyl-N'-(azide-PEG3)-Cy3
- Purity
- 97%
- Packaging
- 10mg
- Price
- $680
- Updated
- 2021/12/16
N-methyl-N'-(azide-PEG3)-Cy3 Chemical Properties,Usage,Production
Description
N-methyl-N'-(azide-PEG3)-Cy3 is a PEG linker containing cyanine dye with excitation/emmission maximum 555/570 nm as well as an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media.
Uses
N-methyl-N'-(azide-PEG3)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-methyl-N'-(azide-PEG3)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-methyl-N'-(azide-PEG3)-Cy3 Preparation Products And Raw materials
Raw materials
Preparation Products
N-methyl-N'-(azide-PEG3)-Cy3 Suppliers
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