ChemicalBook > CAS DataBase List > 4-ISOPROPOXYBENZALDEHYDE

4-ISOPROPOXYBENZALDEHYDE

Product Name: 4-ISOPROPOXYBENZALDEHYDE
CAS No.: 18962-05-5
Chemical Name: 4-ISOPROPOXYBENZALDEHYDE
Synonyms: NSC 69072;AKOS 226-45;AKOS BC-2523;AKOS B000275;ALDH1A3-IN-3;ASISCHEM R42745;BUTTPARK 32\08-27;4-IsopropoxybenzaL;4-ISOPROPOXYBENZALDEHYDE;p-Isopropoxybenzaldehyde
CBNumber: CB9318261
Molecular Formula: C10H12O2
Formula Weight: 164.2
MOL File: 18962-05-5.mol

Less

4-ISOPROPOXYBENZALDEHYDE Property

Melting point:: 167 °C
Boiling point:: 108-110 °C (5 mmHg)
Density: 1.036
refractive index: 1.545-1.547
Flash point:: 108-110°C/5mm
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: clear liquid
color: Colorless to Light orange to Yellow
Sensitive: Air Sensitive
BRN: 742921
InChI: InChI=1S/C10H12O2/c1-8(2)12-10-5-3-9(7-11)4-6-10/h3-8H,1-2H3
InChIKey: WDANSDASCKBVKH-UHFFFAOYSA-N
SMILES: C(=O)C1=CC=C(OC(C)C)C=C1
CAS DataBase Reference: 18962-05-5(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26-36
HazardClass: IRRITANT
HS Code: 2912490090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: I0949
Product name: 4-Isopropoxybenzaldehyde
Purity: >96.0%(GC)
Packaging: 5g
Price: $48
Updated: 2025/07/31

TCI Chemical

Product number: I0949
Product name: 4-Isopropoxybenzaldehyde
Purity: >96.0%(GC)
Packaging: 25g
Price: $167
Updated: 2025/07/31

TRC

Product number: I779023
Product name: 4-Isopropoxybenzaldehyde
Packaging: 250mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: J52199
Product name: 4-Isopropoxybenzaldehyde
Packaging: 1g
Price: $10
Updated: 2021/12/16

Matrix Scientific

Product number: 028456
Product name: 4-Isopropoxybenzaldehyde
Purity: 95+%
Packaging: 5g
Price: $17
Updated: 2021/12/16

Less

4-ISOPROPOXYBENZALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Uses

ALDH1A3-IN-3 (compound 16) is a potent inhibitor of ALDH1A3, with an IC50 of 0.26 μM. ALDH1A3-IN-3 is also a good ALDH3A1 substrate. ALDH1A3-IN-3 can be used for the research of prostate cancer[1].

Synthesis

75-30-9

123-08-0

18962-05-5

General procedure for the synthesis of 4-isopropoxybenzaldehyde from 2-iodopropane and p-hydroxybenzaldehyde: Referring to Example 3, to a 100 mL DMF solution containing 2 g (16.38 mmol) of p-hydroxybenzaldehyde was added sequentially 2.72 g (19.69 mmol) of K2CO3, 2.74 g (16.52 mmol) of KI, and 3.94 mL ( 39.38 mmol) 2-iodopropane and the reaction was carried out under argon protection. The reaction mixture was stirred at 80 °C overnight and subsequently concentrated. The concentrated residue was partitioned between CHCl3 and H2O to separate the organic and aqueous phases. The aqueous phase was further extracted with CHCl3 and after combining all the organic phases was dried and concentrated with MgSO4. The crude product was purified by silica gel column chromatography using a gradient polarity EtOAc/hexane mixed solvent as eluent, resulting in 2.08 g of oily 4-isopropoxybenzaldehyde in 77% yield. The structure of the product was confirmed by 1H-NMR (300 MHz, CDCl3, δTMS): 1.39 (d, J=6Hz, 6H), 4.67 (m, 1H), 6.96 (d, J=8.7Hz, 2H), 7.81 (d, J=8.7Hz, 2H), 9.87 (s, 1H).

IC 50

ALDH3; ALDH1

References

[1] Ibrahim AIM, et, al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848. DOI:10.1021/acs.jmedchem.1c01367

4-ISOPROPOXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-ISOPROPOXYBENZALDEHYDE Suppliers

Americas 1 Belgium 1 China 109 Europe 2 Germany 4 India 13 Japan 2 Slovakia 1 Switzerland 2 Ukraine 2 United Kingdom 19 United States 26 Global 182

Shanghai Fine Biotech Co.，Ltd

Tel: 18717800556
Email: sales@finebiotech.com
Country: China
ProdList: 2182
Advantage: 58

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Changzhou Bestar Industry Co.,Ltd.

Tel: 0519-82309982
Fax: 0519-82309985
Country: China
ProdList: 129
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Nanjing NingFan Pharm-Tech CO. LTD.

Tel: 17368696818
Country: China
ProdList: 1984
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10267
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Baoji Guokang Healthchem Co., Ltd.

Tel: +86-0917-3909592 +86-13892490616
Fax: 09173909592
Email: gksales1@gk-bio.com
Country: China
ProdList: 9209
Advantage: 58

Shanghai TenSus Biotechnology Co., Ltd.

Tel: 021-50895067 18616507272
Fax: 021-50895067
Email: tensus@163.com
Country: China
ProdList: 8073
Advantage: 58

Tianjin and Sinde Biotechnology Co., Ltd.

Tel: 15022315965; 18502259037
Email: sales_hxd@163.com
Country: China
ProdList: 509
Advantage: 58

Xinyi Huaju Pharmaceutical Technology Co., Ltd.

Tel: 13761372795
Email: huajupharm@163.com
Country: China
ProdList: 806
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Beijing Haite lesk Technology Co., Ltd

Tel: 15210893940; 15116916250
Fax: QQ: 237008221
Email: chemistryliu@163.com
Country: China
ProdList: 7327
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Shanghai Yunfu Nano Technology Co., Ltd

Tel: 18964169089
Email: yfnano@126.com
Country: China
ProdList: 4546
Advantage: 58

Yuzhou Enthalpy Carbon Pharmaceutical Technology Co. LTD

Tel: 19963477321; 19963477321
Fax: QQ:2041275825
Email: 2041275825@qq.com
Country: China
ProdList: 1447
Advantage: 58

Qingfeng Chem

Tel: 18672943286
Email: brian_zhao@whqfchem.com
Country: China
ProdList: 440
Advantage: 58

Shanghai Hecheng Medical Technology Co., LTD

Tel: 13564747822
Fax: QQ774046800
Email: 669027880@qq.com
Country: China
ProdList: 924
Advantage: 58

Hebei Zhentian Food Additives Co., Ltd.

Tel: 0551-77777777-5 13333333333
Fax: 0319 5925599
Country: China
ProdList: 9998
Advantage: 58

Jiangxi ravel Biotechnology Co.,Ltd

Tel: 400-880-2824; 13184580281
Fax: 400-880-2824
Email: hj@ruiweier.cn
Country: China
ProdList: 2686
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Qi Qi hang Biotechnology Co., Ltd.

Tel: 15870833005
Email: 2232044025@qq.com
Country: China
ProdList: 8206
Advantage: 58

AAB-PHARMA LIMITED

Tel: 02566880956
Email: 3325708371@qq.com
Country: China
ProdList: 7869
Advantage: 58

Huaihua Baohua Biological Technology Co. LTD

Tel: 0519-82698292
Email: info@hhbhswkj.com
Country: China
ProdList: 134
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Less

View Lastest Price from 4-ISOPROPOXYBENZALDEHYDE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-ISOPROPOXYBENZALDEHYDE 18962-05-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-ISOPROPOXYBENZALDEHYDE 18962-05-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 4-(Isopropyloxy)benzaldehyde 18962-05-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-09

18962-05-5, 4-ISOPROPOXYBENZALDEHYDERelated Search:

4-ISOPROPOXYBENZOIC ACID P-CYCLOHEXYLOXYBENZOIC ACID 2,2-DIMETHYLCHROMANE-6-CARBALDEHYDE 4-ISOPROPOXYBENZALDEHYDE Rotenone 4-(TERT-BUTOXY)BENZALDEHYDE 2-ISO-PROPOXYBENZALDEHYDE 4-(TERT-BUTOXY)BENZOIC ACID OSAJIN ISO-OSAJIN 2-(4-CARBOXYPHENOXY)-2-PIVALOYL-2',4'-DICHLOROACETANILIDE 4-ISO-PROPOXY-BENZOYL CHLORIDE 4-ISOPROPOXYBENZOIC ACID METHYL ESTER 3-CHLORO-5-ETHOXY-4-ISOPROPOXYBENZALDEHYDE 5-CHLORO-2-ISOPROPOXYBENZALDEHYDE 3-BROMO-4-ISOPROPOXYBENZALDEHYDE 3-ALLYL-5-ETHOXY-4-ISOPROPOXYBENZALDEHYDE 5-bromo-3-iodo-2-isopropoxybenzaldehyde

ASISCHEM R42745

BUTTPARK 32\08-27

4-ISOPROPOXYBENZALDEHYDE

AKOS B000275

AKOS 226-45

AKOS BC-2523

4-ISOPROPOXY-1-FORMYLBENZENE

4-Isopropoxybenzaldehyde,98%

4-isopropoxybenzaldehyde(SALTDATA: FREE)

4-(1-Methylethoxy)benzaldehyde

4-(Isopropyloxy)benzaldehyde

4-(Propan-2-yloxy)benzaldehyde

4-[(1-Methylethyl)oxy]benzaldehyde

NSC 69072

p-(Isopropyloxy)benzaldehyde

p-Isopropoxybenzaldehyde

4-IsopropoxybenzaL

4-Isopropoxybenzaldehyde &gt

Benzaldehyde, 4-(1-methylethoxy)-

ALDH1A3-IN-3

18962-05-5

18962-05-0

18963-05-5

ALDEHYDE

Aromatic Aldehydes & Derivatives (substituted)