ChemicalBook > CAS DataBase List > Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI)
Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI)
- Product Name
- Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI)
- CAS No.
- 125391-75-5
- Chemical Name
- Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI)
- Synonyms
- 2-Amino-3'-deoxy-3'-fluoroadenosine;2-Amino-3’-deoxy-3’-fluoroadenosine;ADENOSINE, 2-AMINO-3'-DEOXY-3'-FLUORO-;Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI);(2R,3S,4S,5R)-2-(2,6-diamino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
- CBNumber
- CB93184751
- Molecular Formula
- C10H13FN6O3
- Formula Weight
- 284.25
- MOL File
- 125391-75-5.mol
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Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI) Property
- InChI
- InChI=1S/C10H13FN6O3/c11-4-3(1-18)20-9(6(4)19)17-2-14-5-7(12)15-10(13)16-8(5)17/h2-4,6,9,18-19H,1H2,(H4,12,13,15,16)/t3-,4-,6-,9-/m1/s1
- InChIKey
- BBWXIJICDDYYJZ-DXTOWSMRSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C3C(=C(N=C(N)N=3)N)N=C2)[C@H](O)[C@@H]1F
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Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI) Chemical Properties,Usage,Production
Uses
2-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
Adenosine,2-amino-3'-deoxy-3'-fluoro- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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