ChemicalBook > CAS DataBase List > 2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE

2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE

Product Name
2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE
CAS No.
54458-61-6
Chemical Name
2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE
Synonyms
2-Cyclopenten-1-one, 2,3,4,5-tetramethyl-;2,3,4,5-TETRAMETHYLCYCLOPENT-2-ENONE;opentenone;Zinc02003168;Zinc02003169;Zinc02003171;Zinc02003172;2,3,4,5-TetramethyL;2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE;2,3,4,5-tetramethyl-2-cyclopentanone
CBNumber
CB9325814
Molecular Formula
C9H14O
Formula Weight
138.21
MOL File
54458-61-6.mol
More
Less

2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE Property

Boiling point:
100 °C30 mm Hg(lit.)
Density 
0.927 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.476
Flash point:
164 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol
form 
Oil
color 
Clear Colourless
Specific Gravity
0.917
Water Solubility 
Not miscible with water.
BRN 
2324088
InChI
InChI=1S/C9H14O/c1-5-6(2)8(4)9(10)7(5)3/h5,7H,1-4H3
InChIKey
ARUAYSANQMCCEN-UHFFFAOYSA-N
SMILES
C1(=O)C(C)C(C)C(C)=C1C
CAS DataBase Reference
54458-61-6(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
23-24/25-35-3/9/49-43-36-15
WGK Germany 
3
HS Code 
29142990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P403+P235Store in a well-ventilated place. Keep cool.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
274658
Product name
2,3,4,5-Tetramethyl-2-cyclopentenone, mixture of cis and trans
Purity
95%
Packaging
5g
Price
$76.3
Updated
2024/03/01
Sigma-Aldrich
Product number
274658
Product name
2,3,4,5-Tetramethyl-2-cyclopentenone, mixture of cis and trans
Purity
95%
Packaging
25g
Price
$92
Updated
2024/03/01
Alfa Aesar
Product number
L09617
Product name
2,3,4,5-Tetramethyl-2-cyclopentenone, cis + trans, 95%
Packaging
5g
Price
$66.65
Updated
2024/03/01
Alfa Aesar
Product number
L09617
Product name
2,3,4,5-Tetramethyl-2-cyclopentenone, cis + trans, 95%
Packaging
25g
Price
$227.65
Updated
2024/03/01
TRC
Product number
T302010
Product name
2,3,4,5-Tetramethyl-2-cyclopenten-1-one
Packaging
5g
Price
$70
Updated
2021/12/16
More
Less

2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE Chemical Properties,Usage,Production

Uses

2,3,4,5-Tetramethyl-2-cyclopentenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Uses

2,3,4,5-Tetramethyl-2-cyclopentenone was used in the synthesis of chiral pre-ligands, (R)-3,3?-bis(tetramethylcyclopentadienyl)-2,2?-bismethoxy-1,1?-bisnaphthalene and (R)-3-tetramethylcyclopentadienyl-2,2?-bismethoxy-1,1?-bisnaphthalene by reacting with (R)-3,3?-dilithium-2,2?-bismethoxy-1,1?-bisnaphthalene.

Synthesis


In a bottom round flask equipped with a mechanical stirrer, a dropping funnel and a reflux condenser was loaded 2000g (23.2 mol) of the starting ketone with 75% w/w of butylacetate as the solvent, 0.35 molar equivalents of anhydrous magnesium chloride and the aforementioned titanium catalytic solution containing 0.06 molar equivalents of the trichloropropoxytitanium complex. The resulting suspension was stirred vigorously and allowed to heat to 90°C. Then 2 molar equivalents of the acetaldehyde were added dropwise over 3h at 90°C. The reaction was continued for an additional hour and cooled to 40°C. The reaction mixture was hydrolysed with a 10% aqueous acetic acid solution and neutralised with a 20% aqueous potassium carbonate solution. The resulting organic phase was directly fractionated into a laboratory Sulzer packed column, to afford the title compound, as a mixture of isomers trans:cis = 85:15, in 27 % yield and the enone (II) (i.e. 4-methyl-4-hexen-3-one) in 31 % yield. mixture of isomers trans:cis = (B.p. = 70-80°C at P = 8 mbar); 4-methyl-4-hexen-3-one = (B.p. = 45-65°C at P = 8 mbar). 1H-NMR (isomer trans): 1.15 (d 3H); 1.19 (d 3H); 1.68 (s 3H); 1.88 (m 1H); 1.98 (s 3H); 2.25 (m 1H). 13C-NMR (isomer trans): 8.5; 14.6; 15.1 ; 17.7; 46.2; 48.4; 134.5; 171.6; 21 1.0.

2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE Preparation Products And Raw materials

Raw materials

Preparation Products

1,2,3,4-TETRAMETHYL-1,3-CYCLOPENTADIENE
More
Less

2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE Suppliers

China 178 Germany 5 India 6 Japan 2 Russia 1 Switzerland 1 The Netherlands 1 United Kingdom 3 United States 11 Global 208
Nanjing Tianyi Chemical Technology Co., Ltd
Tel
15150528611
Fax
151-5052-8611
Email
779881375@qq.com
Country
China
ProdList
72
Advantage
58
Mascot I.E. Co., Ltd
Tel
0519-85010339 13584504415
Fax
0519-85010366
Email
info@mascot-ie.com
Country
China
ProdList
190
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 13451648594
Fax
0512-87182056
Email
sales@yacoo.com.cn
Country
China
ProdList
5000
Advantage
58
Shanghai Finechem Biotechnology Co., Ltd.
Tel
15821337685
Email
hwh-chem@163.com
Country
China
ProdList
96
Advantage
58
Hangzhou Xiao Bei Medical Technology Co., LTD
Tel
+86-571-8526 3177 13962438025
Email
beixi.dong@heryipharma.com
Country
China
ProdList
163
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17989
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Tangshan Moneide Trading Co., Ltd.
Tel
0315-8309571 15633399667
Fax
+86-315-7726572
Email
sales@moneidechem.com
Country
China
ProdList
704
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Springchem New Material Technology Co.,Limited
Tel
+86-021-62885108 +8613917661608
Email
info@spring-chem.com
Country
China
ProdList
2068
Advantage
57
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4000
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
Shanghai Arbor Chemical Co., Ltd.
Tel
021-021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
922
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7876
Advantage
55
ShangHai Zexin Chemical Technology Co., Ltd.
Tel
021-60136491 15901897992
Fax
021-60136492
Country
China
ProdList
455
Advantage
55
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
Suzhou Laing Biological Technology Co., LTD
Tel
0512-62968256 18550502935
Fax
0512-62968256
Email
export@laingbiotec.com
Country
China
ProdList
1040
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
HangZhou YuHao Chemical Technology Co., Ltd.
Tel
0571-82693216
Fax
0571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
2031
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Anhui CONO Fine Chemical Co., Ltd.
Tel
0550-0550-7097550 15051613561
Fax
0550-7097550
Email
sales@ahknchem.com
Country
China
ProdList
219
Advantage
60
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Shanghai BLT Biological Pharmaceutical Co., Ltd.
Tel
021-20786057 18918495077
Fax
021-20786057
Email
3116390381@qq.com
Country
China
ProdList
220
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9951
Advantage
58
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6357
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
9859
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13350
Advantage
58
Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.
Tel
027-65526929 15102793023
Fax
027-65526669
Email
hbhxry@163.com
Country
China
ProdList
2060
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
Zhengzhou JACS Chemical Co., Ltd.
Tel
0371-0371-86259281 15981966935
Fax
0371-86259281
Email
jacschem@163.com
Country
China
ProdList
2010
Advantage
58
Capot Chemical Co.,Ltd.
Tel
571-85586718 +8613336195806
Fax
+86-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
29797
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15085
Advantage
58
More
Less

View Lastest Price from 2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE manufacturers

Wuhan Han Sheng New Material Technology Co.，Ltd
Product
2,3,4,5-Tetramethylcyclopent-2-enone 95% 54458-61-6
Price
US $36.48/KG
Min. Order
1KG
Purity
99%
Supply Ability
15MT
Release date
2023-09-21
Wuhan Han Sheng New Material Technology Co.，Ltd
Product
2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE, 95 % 54458-61-6
Price
US $36.47/KG
Min. Order
1KG
Purity
99%
Supply Ability
15MT
Release date
2023-09-21
Wuhan Han Sheng New Material Technology Co.，Ltd
Product
2,3,4,5-TETRAMETHYLCYCLOPENT-2-ENONE 54458-61-6
Price
US $36.46/KG
Min. Order
1KG
Purity
99%
Supply Ability
15MT
Release date
2023-09-21

54458-61-6, 2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONERelated Search:

Cyclopentene 2-Cyclopenten-1-one TRANS-2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE SALOR-INT L162698-1EA SALOR-INT L161136-1EA SALOR-INT L160792-1EA SALOR-INT L162744-1EA 2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE

  • 2,3,4,5-TETRAMETHYL-2-CYCLOPENTEN-1-ONE
  • 2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE
  • 2,3,4,5-TETRAMETHYLCYCLOPENT-2-ENONE
  • 2,3,4,5-Tetramethyl-2-cyclopentenone (mixture of cis- and trans- isomers),
  • 2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE, 95 %, MIXTURE OF CIS AND TRANS
  • 2,3,4,5-tetramethyl-2-cyclopentenone, cis + trans
  • 2,3,4,5-tetramethyl-2-cyclopentenone, mixture of cis and trans
  • 2,3,4,5-Tetramethylcyclopent-2-enone 95%
  • 2,3,4,5-tetramethyl-2-cyclopentanone (cis+trans)
  • 2,3,4,5-Tetramethylcyclopenta-2-ene-1-one
  • 2,3,4,5-Tetramethyl-2-cyclopentenone (mixture of cis- and trans- isomers), 97+%
  • Zinc02003168
  • Zinc02003169
  • Zinc02003171
  • Zinc02003172
  • trans-2,3,4,5-tetraMethylcyclopent-2-enone
  • 2,3,4,5-tetramethyl-2-cyclopentanone
  • 2,3,4,5-Tetramethyl-2-cyclopentenone, mixture of cis and trans 95%
  • 2,3,4,5-TetramethyL
  • opentenone
  • 2-Cyclopenten-1-one, 2,3,4,5-tetramethyl-
  • 2,3,4,5-Tetramethyl 2-cyclopentenone Cis + Trans--95%
  • 2,3,4,5-Tetramethylcyclopent-2-enone,mixture of cis and trans
  • 54458-61-6 2,3,4,5-TETRAMETHYL-2-CYCLOPENTENONE
  • 2,3,4,5-Tetramethyl-2-cyclopentenone,95%
  • 2,3,4,5-tetramethyl-cyclopenten-2-one
  • 54458-61-6
  • 458-61-6
  • Organic Building Blocks
  • Ketones
  • Carbonyl Compounds
  • C9
  • Building Blocks
  • C9
  • Carbonyl Compounds
  • Ketones
  • 000-111