4-Aminopiperidine Property

Melting point:

25 °C

Boiling point:

65°C 18mm

Density 

0.945 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.4910(lit.)

Flash point:

>230 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

form 

Powder

pka

10.37±0.20(Predicted)

color 

Off-white to yellow

Sensitive 

Hygroscopic

BRN 

1105

CAS DataBase Reference

13035-19-3(CAS DataBase Reference)

Safety

Hazard Codes 

C,Xi

Risk Statements 

10-34

Safety Statements 

16-23-26-36/37/39-45-6

RIDADR 

UN 2920 8/PG 2

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

3

PackingGroup 

III

HS Code 

29333990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-Aminopiperidine Chemical Properties,Usage,Production

Uses

Reactant for synthesis of 4-Aminopiperidine:

• Cdk5/p25 kinase inhibitors
• Antimalarials
• Selective cyclin-dependent kinase 4/6 inhibitors
• IKKβ inhibitors
• Orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation
• Human and murine soluble epoxide hydrolase inhibitors

Uses

Reactant for synthesis of:

• Cdk5/p25 kinase inhibitors
• Antimalarials
• Selective cyclin-dependent kinase 4/6 inhibitors
• IKKβ inhibitors
• Orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation
• Human and murine soluble epoxide hydrolase inhibitors