ChemicalBook > CAS DataBase List > UK-371804 hydrochloride

UK-371804 hydrochloride

Product Name
UK-371804 hydrochloride
CAS No.
256476-36-5
Chemical Name
UK-371804 hydrochloride
Synonyms
UK-371804 HCl;UK-371804 hydrochloride;UK371804 HCl,UK 371804 HCl;UK-371,804 HCl >=98% (HPLC);2-((4-Chloro-1-guanidinoisoquinoline)-7-sulfonamido)-2-methylpropanoic acid hydrochloride
CBNumber
CB93313256
Molecular Formula
C14H17Cl2N5O4S
Formula Weight
422.28
MOL File
256476-36-5.mol
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UK-371804 hydrochloride Property

Melting point:
258 °C (decomp)
storage temp. 
-20°C
solubility 
DMSO: 42 mg/mL (99.46 mM);Ethanol: Insoluble
form 
powder
color 
white to beige
Water Solubility 
Water: Insoluble
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PZ0344
Product name
UK-371,804 HCl
Purity
≥98% (HPLC)
Packaging
5mg
Price
$105
Updated
2024/03/01
Sigma-Aldrich
Product number
PZ0344
Product name
UK-371,804 HCl
Purity
≥98% (HPLC)
Packaging
25mg
Price
$338
Updated
2024/03/01
AK Scientific
Product number
8759CW
Product name
UK-371,804 HCl
Packaging
5mg
Price
$127
Updated
2021/12/16
AK Scientific
Product number
8759CW
Product name
UK-371,804 HCl
Packaging
25mg
Price
$266
Updated
2021/12/16
Crysdot
Product number
CD31004930
Product name
UK-371,804 HCl
Purity
99+%
Packaging
25mg
Price
$188
Updated
2021/12/16
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UK-371804 hydrochloride Chemical Properties,Usage,Production

Biochem/physiol Actions

UK-371,804 is a reversible, substrate-competitive, highly potent (Ki = 10 nM) and selective urokinase-type plasminogen activator (uPA) Inhibitor with excellent selectivity over tPA, plasmin, Factor IXa and Xa. When applied topically, UK-371,80 effectively penetrates into excisional wounds of experimental pigs with no adverse effect on wound closure. UK-371,804 effectively blocks EGR-FMK from binding human uPA even in the presence of tissue proteins.

UK-371804 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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UK-371804 hydrochloride Suppliers

Shanghai Boyle Chemical Co., Ltd.
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Fax
86-21-57758967
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China
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Sigma-Aldrich
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Shanghai Biopharmaleader Co., Ltd.
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Twochem Co.Ltd.
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TargetMol Chemicals Inc.
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United States
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256476-36-5, UK-371804 hydrochlorideRelated Search:


  • UK-371804 hydrochloride
  • UK-371804 HCl
  • UK-371,804 HCl >=98% (HPLC)
  • 2-((4-Chloro-1-guanidinoisoquinoline)-7-sulfonamido)-2-methylpropanoic acid hydrochloride
  • UK371804 HCl,UK 371804 HCl
  • 256476-36-5