JNJ-42259152
- Product Name
- JNJ-42259152
- CAS No.
- 1301167-87-2
- Chemical Name
- JNJ-42259152
- Synonyms
- JNJ-42259152;Pyridine, 2-[[4-[1-(2-fluoroethyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-3,5-dimethyl-
- CBNumber
- CB93333737
- Molecular Formula
- C24H23FN4O
- Formula Weight
- 402.46
- MOL File
- 1301167-87-2.mol
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JNJ-42259152 Property
- Melting point:
- 138.8 °C
- Boiling point:
- 558.0±50.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- pka
- 4.37±0.32(Predicted)
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JNJ-42259152 Chemical Properties,Usage,Production
Uses
JNJ-42259152 is a phosphodiesterase 10A (PDE10A) positron emission tomography (PET) tracer that is specific for PDE10A activity. JNJ-42259152 can be dynamically scanned in healthy volunteers to assess its kinetic properties in the brain. The half-life of JNJ-42259152 in the blood is an average of 90 minutes. JNJ-42259152 has demonstrated reliable binding potential (BPND) in different target areas (such as the lentiform nucleus, caudate nucleus, ventral striatum, etc.), providing an important tool for studying neuropsychiatric diseases[1].
References
[1] Quantification of 18F-JNJ-42259152, a novel phosphodiesterase 10A PET tracer: kinetic modeling and test-retest study in human brain DOI:10.2967/jnumed.112.118679
JNJ-42259152 Preparation Products And Raw materials
Raw materials
Preparation Products
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JNJ-42259152 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
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- 32435
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- 15002134094
- marketing@targetmol.cn
- Country
- China
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