2'-O,4'-C-Methylenecytidine
- Product Name
- 2'-O,4'-C-Methylenecytidine
- CAS No.
- 206055-69-8
- Chemical Name
- 2'-O,4'-C-Methylenecytidine
- Synonyms
- 2'-O,4'-C-Methylenecytidine;Cytidine, 2'-O,4'-C-methylene-;2’-O,4’-C-Methylenecytidine, LNA-C
- CBNumber
- CB93334224
- Molecular Formula
- C10H13N3O5
- Formula Weight
- 255.23
- MOL File
- 206055-69-8.mol
2'-O,4'-C-Methylenecytidine Property
- storage temp.
- Store at -20°C
- form
- Solid
- color
- White to off-white
2'-O,4'-C-Methylenecytidine Chemical Properties,Usage,Production
Uses
2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].
Biological Activity
2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].
References
[1]. bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes [2]. Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.
2'-O,4'-C-Methylenecytidine Preparation Products And Raw materials
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