3'-Azido-3'-deoxy-beta-L-cytidine

Product Name: 3'-Azido-3'-deoxy-beta-L-cytidine
CAS No.: 2095417-59-5
Chemical Name: 3'-Azido-3'-deoxy-beta-L-cytidine
Synonyms: 3'-Azido-3'-deoxy-b-L-cytidine;3’-Azido-3’-deoxy-β-L-cytidine;3'-Azido-3'-deoxy-beta-L-cytidine;3’-Azido-3’-deoxy-beta-L-cytidine;4-{5-[2-(2-Methyl-furan-3-yl)-6-oxo-thiazolo[3,2-b][1,2,4]triazol-5-ylidenemethyl]-furan-2-yl}-benzenesulfonamide
CBNumber: CB93334239
Molecular Formula: C9H12N6O4
Formula Weight: 268.23
MOL File: 2095417-59-5.mol

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3'-Azido-3'-deoxy-beta-L-cytidine Chemical Properties,Usage,Production

Uses

3’-Azido-3’-deoxy-beta-L-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-Azido-3’-deoxy-beta-L-cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

3'-Azido-3'-deoxy-beta-L-cytidine Preparation Products And Raw materials

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2095417-59-5, 3'-Azido-3'-deoxy-beta-L-cytidineRelated Search:

3'-Azido-3'-deoxy-beta-L-cytidine

3’-Azido-3’-deoxy-β-L-cytidine

3'-Azido-3'-deoxy-b-L-cytidine

3’-Azido-3’-deoxy-beta-L-cytidine

4-{5-[2-(2-Methyl-furan-3-yl)-6-oxo-thiazolo[3,2-b][1,2,4]triazol-5-ylidenemethyl]-furan-2-yl}-benzenesulfonamide

2095417-59-5