ChemicalBook > CAS DataBase List > Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride
Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride
- Product Name
- Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride
- CAS No.
- 63236-23-7
- Chemical Name
- Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride
- Synonyms
- Pareptide monohydrochloride;Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride
- CBNumber
- CB93339658
- Molecular Formula
- C14H27ClN4O3
- Formula Weight
- 334.84218
- MOL File
- 63236-23-7.mol
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Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
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Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride Chemical Properties,Usage,Production
Uses
Pareptide monohydrochloride is a melanotropin-inhibiting factor (MIF) metabolically stable analogue.
in vivo
Chronic coadministration of Pareptide (0.25 mg/kg, SC, BID, 3.5 days) to mice pretreated with Haloperidol (8.0 mg/kg, IP, BID, 3 days) significantly increases the cataleptic effects of a smaller challenge dose of Haloperidol (2.0 mg/kg, IP) given 15 hours after the last pretreatment injections (p<0.01)[1].
References
[1] Mycroft FJ, et al. Pro-Leu-Gly-NH2 and Pareptide inhibit development of tolerance to Haloperidol catalepsy in the mouse. Peptides. 1984 Sep-Oct;5(5):883-7. DOI:10.1016/0196-9781(84)90111-6
Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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Glycinamide, L-prolyl-N-methyl-D-leucyl-, monohydrochloride Suppliers
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