NNC45-0781

Product Name: NNC45-0781
CAS No.: 207277-66-5
Chemical Name: NNC45-0781
Synonyms: NNC45-0781;NNC45 0781,NNC-45-0781,NNC450781;2H-1-Benzopyran-7-ol, 3,4-dihydro-3-phenyl-4-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (3S,4R)-
CBNumber: CB93339683
Molecular Formula: C27H29NO3
Formula Weight: 415.52
MOL File: 207277-66-5.mol

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NNC45-0781 Property

Boiling point:: 563.7±50.0 °C(Predicted)
Density: 1.185±0.06 g/cm3(Predicted)
pka: 9.87±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

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NNC45-0781 Chemical Properties,Usage,Production

Uses

NNC45-0781 is a tissue-selective estrogen partial-agonist.

in vivo

NNC45-0781 (NNC 45-0781) shows that it is a very promising tissue-selective estrogen agonist. Total serum cholesterol is significantly increased in the vehicle-treated group as compared to the sham animals. All of the animals receiving NNC45-0781 at doses of 10 nmol/g or higher, has significantly lower levels of total serum cholesterol as compared to the vehicle treated group^[1].

References

[1] Bury PS, et al. Synthesis and pharmacological evaluation of novel cis-3,4-diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor. Bioorg Med Chem. 2002 Jan;10(1):125-45. DOI:10.1016/s0968-0896(01)00257-7

NNC45-0781 Preparation Products And Raw materials

Raw materials

Preparation Products

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NNC45-0781 Suppliers

China 3 United States 5 Global 8

MedChemexpress LLC

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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207277-66-5, NNC45-0781Related Search:

NNC45-0781

2H-1-Benzopyran-7-ol, 3,4-dihydro-3-phenyl-4-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (3S,4R)-

NNC45 0781,NNC-45-0781,NNC450781

207277-66-5