N3-PEG3-CH2COOtBu

Product Name: N3-PEG3-CH2COOtBu
CAS No.: 172531-36-1
Chemical Name: N3-PEG3-CH2COOtBu
Synonyms: Azido-PEG3-C-Boc;N3-PEG3-CH2COOtBu;Azido-PEG3-CH2COOtBu;Azido-PEG3-CH2CO2-t-Bu;azidotriethyleneglycol-Boc;Azido-PEG3-CH2COOH t-Bu Ester;Azido-PEG3-CH2CO2-t-butyl ester;tert-Butyl 11-azido-3,6,9-trioxaundecanoate;tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate;N3-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber: CB93340577
Molecular Formula: C12H23N3O5
Formula Weight: 289.32812
MOL File: 172531-36-1.mol

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N3-PEG3-CH2COOtBu Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific

Product number: AMTGC501
Product name: 1,1-Dimethylethyl11-azido-3,6,9-trioxaundecanoate
Packaging: 250mg
Price: $128
Updated: 2021/12/16

BroadPharm

Product number: BP-23524
Product name: Azido-PEG3-CH2CO2-t-Bu
Purity: 98%
Packaging: 100mg
Price: $270
Updated: 2021/12/16

AK Scientific

Product number: AMTGC501
Product name: 1,1-Dimethylethyl11-azido-3,6,9-trioxaundecanoate
Packaging: 1g
Price: $334
Updated: 2021/12/16

Activate Scientific

Product number: AS104041
Product name: N3-PEG3-CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $361
Updated: 2021/12/16

Acrotein

Product number: B-0920
Product name: N3-PEG3-CH2COOtBu
Purity: 97%
Packaging: 1g
Price: $247.5
Updated: 2021/12/16

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N3-PEG3-CH2COOtBu Chemical Properties,Usage,Production

Description

Azido-PEG3-CH2CO2-t-Bu is a N3 (azide) containing t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Azido-PEG3-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-C-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N3-PEG3-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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N3-PEG3-CH2COOtBu Suppliers

China 31 United States 2 Global 33

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
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Country: China
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Borenpharm Co., Ltd

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Fax: 86-27-59218822
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Country: China
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Jinan elephant international trading co., LTD

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Email: 13006575422@163.com
Country: China
ProdList: 6355
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Amatek Scientific Co. Ltd.

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Shandong utilizing biological technology co., LTD

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TargetMol Chemicals Inc.

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Nextpeptide Inc

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Xiamen Sinopeg Biotech Co., Ltd.

Tel: 400-9189898 17359873007
Email: sales@sinopeg.com
Country: China
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View Lastest Price from N3-PEG3-CH2COOtBu manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: N3-PEG3-CH2COOtBu 172531-36-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-04

172531-36-1, N3-PEG3-CH2COOtBuRelated Search:

N3-PEG3-CH2COOtBu

Azido-PEG3-CH2CO2-t-butyl ester

Azido-PEG3-CH2CO2-t-Bu

tert-Butyl 11-azido-3,6,9-trioxaundecanoate

Azido-PEG3-C-Boc

azidotriethyleneglycol-Boc

Azido-PEG3-CH2COOtBu

tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate

Azido-PEG3-CH2COOH t-Bu Ester

N3-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester

172531-36-1