Nolomirole hydrochloride
- Product Name
- Nolomirole hydrochloride
- CAS No.
- 138531-51-8
- Chemical Name
- Nolomirole hydrochloride
- Synonyms
- CHF1035;CHF 1035;CHF-1035;Nolomirole HCl;Nolomirole hydrochloride
- CBNumber
- CB93355414
- Molecular Formula
- C19H28ClNO4
- Formula Weight
- 369.89
- MOL File
- 138531-51-8.mol
Nolomirole hydrochloride Chemical Properties,Usage,Production
Description
Nolomirole HCl is a Dopamine Receptor Agonist. Nolomirole is able to attenuate the heart failure signs in the monocrotaline-induced congestive heart failure.
Uses
Nolomirole (CHF 1035) hydrochloride is an orally active and selective DA2 dopaminergic receptor/α2-adrenoceptor agonist. Nolomirole attenuates the heart failure signs in the Monocrotaline (HY-N0750)-induced congestive heart failure model. Nolomirole increases cardiac output[1][2].
References
[1] Pasini E, et al. Effect of nolomirole on monocrotaline-induced heart failure. Pharmacol Res. 2004 Jan;49(1):1-5. DOI:10.1016/s1043-6618(03)00246-9
[2] Torp-Pedersen C, et al. A randomised trial of a pre-synaptic stimulator of DA2-dopaminergic and alpha2-adrenergic receptors on morbidity and mortality in patients with heart failure. Eur J Heart Fail. 2008 Jan;10(1):89-95. DOI:10.1016/j.ejheart.2007.10.012
Nolomirole hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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