ChemicalBook > CAS DataBase List > CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)

CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)

Product Name
CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)
CAS No.
228546-92-7
Chemical Name
CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)
Synonyms
FE 200665|||JNJ 38488502;CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl);D-Argininamide, D-phenylalanyl-D-phenylalanyl-D-norleucyl-N-(4-pyridinylmethyl)-
CBNumber
CB93358798
Molecular Formula
C36H49N9O4
Formula Weight
671.83
MOL File
228546-92-7.mol
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CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Property

Density 
1.26±0.1 g/cm3(Predicted)
pka
13.36±0.46(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Chemical Properties,Usage,Production

Uses

CR 665 (JNJ 38488502) is a peripherally selective κ-opioid agonist. CR 665 can activate the kappa opioid receptor with EC50 value of 10.9 nM. CR 665 can be used for the research of peripheral pain[1][2].

References

[1] Anne E Olesen, et al. A population pharmacokinetic and pharmacodynamic study of a peripheral κ-opioid receptor agonist CR665 and oxycodone. Clin Pharmacokinet DOI:10.1007/s40262-012-0023-8
[2] Francis M Hughes Jr, et al. Development of a Peptide-derived orally-active kappa-opioid receptor agonist targeting peripheral pain. Open Med Chem J. 2013 Nov 4;7:16-22. DOI:10.2174/1874104501307010016

CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Preparation Products And Raw materials

Raw materials

Preparation Products

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CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Suppliers

China 10 United States 1 Global 11
Shanghai Chaolan Chemical Technology Center
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021-QQ：65489617 15618227136
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Sales@ATKchemical.com
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Nanjing Leon Biological Technology Co., Ltd.
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17705183659
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84523390
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sales@njleonbiotech.com
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Hangzhou Peptidego Biotech Co.,Ltd.
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0571-87213919
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Eric@peptidego.com
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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Hangzhou Sinoda Pharmaceutical Technology Co. LTD
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0571-87213919 17306812703
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Shanghai HongTide Biotechnology Co.,Ltd.
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15318089928
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YantaiBio
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13758194781 15083780366
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LEON (NANJING) BIOTECHNOLOGY CO., LTD.
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+8615051830413
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Changsha MOL Changes Biotechnology Co., Ltd.
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+8619375158599
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info@molchanges.com
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TargetMol Chemicals Inc.
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+17819995354
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marketing@targetmol.com
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United States
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228546-92-7, CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)Related Search:


  • CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)
  • D-Argininamide, D-phenylalanyl-D-phenylalanyl-D-norleucyl-N-(4-pyridinylmethyl)-
  • FE 200665|||JNJ 38488502
  • 228546-92-7
  • C36H49N9O4