N-(Azido-PEG4)-Biocytin
- Product Name
- N-(Azido-PEG4)-Biocytin
- CAS No.
- 2055042-70-9
- Chemical Name
- N-(Azido-PEG4)-Biocytin
- Synonyms
- N-(Azido-PEG4)-Biocytin
- CBNumber
- CB93363963
- Molecular Formula
- C27H47N7O9S
- Formula Weight
- 645.76858
- MOL File
- 2055042-70-9.mol
N-(Azido-PEG4)-Biocytin Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DMF
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- BP-23286
- Product name
- N-(Azido-PEG4)-biocytin
- Purity
- 98%
- Packaging
- 100mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- BP-23286
- Product name
- N-(Azido-PEG4)-biocytin
- Purity
- 98%
- Packaging
- 500mg
- Price
- $840
- Updated
- 2021/12/16
N-(Azido-PEG4)-Biocytin Chemical Properties,Usage,Production
Description
N-(Azido-PEG4)-biocytin is a biotin PEG linker containing a carboxylic group and an azide group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The azide group can react with alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound.
Uses
N-(Azido-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG4)-biocytin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Azido-PEG4)-Biocytin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-(Azido-PEG4)-Biocytin manufacturers
- Product
- N-(Azido-PEG4)-biocytin 2055042-70-9
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-30