ChemicalBook > CAS DataBase List > CC-671

CC-671

Product Name: CC-671
CAS No.: 1618658-88-0
Chemical Name: CC-671
Synonyms: CC-671;CS-2792;CC-671 (CC671;CC-671, 10 mM in DMSO;Inhibitor,inhibit,Cyclin dependent kinase,CC671,CC-671,CC 671,CDK;4-(4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3-methoxy-N-methylbenzamide;Benzamide, 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-
CBNumber: CB93364612
Molecular Formula: C28H28N6O4
Formula Weight: 512.56
MOL File: 1618658-88-0.mol

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CC-671 Property

Density: 1.351±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:60.0(Max Conc. mg/mL);117.06(Max Conc. mM)
form: A crystalline solid
pka: 12.12±0.50(Predicted)
color: Off-white to light green

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26184
Product name: CC-671
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 26184
Product name: CC-671
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 26184
Product name: CC-671
Packaging: 10mg
Price: $243
Updated: 2024/03/01

TRC

Product number: C227915
Product name: CC-671
Packaging: 10mg
Price: $1050
Updated: 2021/12/16

ChemScene

Product number: CS-8218
Product name: CC-671
Purity: 98.86%
Packaging: 10mg
Price: $1068
Updated: 2021/12/16

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CC-671 Chemical Properties,Usage,Production

Uses

CC-671, is a novel dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) inhibitor for the treatment of triple negative breast cancer initiated from a phenotypic screen.

in vivo

CC-671 (compound 23) demonstrates significant tumor growth inhibition (TGI) ((vehicle -treated/vehicle) ×100%) of 71% at both 10 and 20 mg/kg on a every 3 days (q3d) dosing schedule. The body weight loss (BWL) in the CC-671 treated group (20 mg/kg ) is higher than in the 10 mg/kg group (17% vs 5%)^[1].

IC 50

CLK2: 0.006 μM (IC₅₀)

CC-671 Preparation Products And Raw materials

Raw materials

Preparation Products

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CC-671 Suppliers

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1618658-88-0, CC-671Related Search:

CC-671 (CC671

4-(4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3-methoxy-N-methylbenzamide

CS-2792

CC-671

Inhibitor,inhibit,Cyclin dependent kinase,CC671,CC-671,CC 671,CDK

Benzamide, 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-

CC-671, 10 mM in DMSO

1618658-88-0