N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester)

Product Name: N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester)
CAS No.: 2112731-81-2
Chemical Name: N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester)
Synonyms: QUN 31812;N-(Azido-PEG2)-N-bis(PEG4-Boc);N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester)
CBNumber: CB93373678
Molecular Formula: C36H70N4O14
Formula Weight: 782.9594
MOL File: 2112731-81-2.mol

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N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester) Property

storage temp.: 2-8°C, protect from light
form: Viscous Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23575
Product name: N-(Azido-PEG2)-N-bis(PEG4-t-butylester)
Purity: 98%
Packaging: 250mg
Price: $580
Updated: 2021/12/16

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N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester) Chemical Properties,Usage,Production

Description

N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester) is a branched PEG compound with a terminal azide group. The azide groups is very reactive with alkyne such as DBCO, BCN and propargyl reagnet via Click Chemistry. . The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.

Uses

N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG2)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester) Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester) Suppliers

China 20 United States 3 Global 23

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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TargetMol Chemicals Inc.

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View Lastest Price from N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester) manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-(Azido-PEG2)-N-bis(PEG4-Boc) 2112731-81-2
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-04-02

2112731-81-2, N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester)Related Search:

N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester)

N-(Azido-PEG2)-N-bis(PEG4-Boc)

QUN 31812

2112731-81-2