PROPIONYL-L-CARNITINE HYDROCHLORIDE
- Product Name
- PROPIONYL-L-CARNITINE HYDROCHLORIDE
- CAS No.
- 20064-19-1
- Chemical Name
- PROPIONYL-L-CARNITINE HYDROCHLORIDE
- Synonyms
- L-Propionylcarnitine;(R)-Propionyl Carnitine;PROPIONYL L-CARNITINE HCL;Levocarnitine Propil;L-Carnitine Propionyl Ester;L-CARNITINE:HCL, O-PROPIONYL;Propionyl-L-carnitine solution;PROPIONYL-L-CARNITINE CHLORIDE;Propionyl-L-carnitine >=97.0% (TLC);PROPIONYL-LEVO-CARNITINE HYDROCHLORIDE
- CBNumber
- CB9338050
- Molecular Formula
- C10H19NO4
- Formula Weight
- 217.27
- MOL File
- 20064-19-1.mol
PROPIONYL-L-CARNITINE HYDROCHLORIDE Property
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Very Slightly), Water (Slightly)
- form
- Semi-Solid to Solid
- color
- Colourless to Off-White
- optical activity
- [α]/D -23±3°, c = 1 in H2O
- Stability:
- Hygroscopic
N-Bromosuccinimide Price
- Product number
- 42602
- Product name
- Propionyl-L-carnitine
- Purity
- ≥94.0% (HPLC)
- Packaging
- 10MG
- Price
- $101
- Updated
- 2023/06/20
- Product number
- 42602
- Product name
- Propionyl-L-carnitine
- Purity
- ≥94.0% (HPLC)
- Packaging
- 50MG
- Price
- $381
- Updated
- 2023/06/20
- Product number
- HCH0014341
- Product name
- (R)-3-CARBOXY-N,N,N-TRIMETHYL-2-(1-OXOPROPOXY)-1-PROPANAMINIUM INNER SALT
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $945.95
- Updated
- 2021/12/16
- Product number
- HCH0014341
- Product name
- (R)-3-CARBOXY-N,N,N-TRIMETHYL-2-(1-OXOPROPOXY)-1-PROPANAMINIUM INNER SALT
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1370.41
- Updated
- 2021/12/16
PROPIONYL-L-CARNITINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
L-Propionyl carnitine has been shown to improve the heart mechanical recovery and other metabolic parameters after ischemia-reperfusion
Uses
Propionyl-L-carnitine was identified in the drinking water in rats.
Uses
Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Definition
ChEBI: O-propanoyl-L-carnitine is an optically active O-acylcarnitine compound having propanoyl as the acyl substituent and (R)-configuration at the 3-position. It has a role as a peripheral nervous system drug. It is an O-propanoylcarnitine and a saturated fatty acyl-L-carnitine.
General Description
Propionyl-L-carnitine (PLC), a natural odd-carbon-number, endogenous ester of L-carnitine, is found to be present in humans and animals as a minor component compared to L-carnitine (LC) and acetyl-L-carnitine (ALC). It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.
Biochem/physiol Actions
Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.