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tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate

Product Name
tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate
CAS No.
143225-31-4
Chemical Name
tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate
Synonyms
FosamprevirImpurity4;Fosamprenavir Impurity 6;Fosamprenavir Impurity 4;tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate;1,1-Dimethylethyl Ester [(1S,2S)-2-Hydroxy-3-[(2-methylpropyl)amino]-1-(phenylmethyl)propyl]carbamic Acid;Carbamic acid, N-[(1S,2S)-2-hydroxy-3-[(2-methylpropyl)amino]-1-(phenylmethyl)propyl]-, 1,1-dimethylethyl ester
CBNumber
CB93393881
Molecular Formula
C19H32N2O3
Formula Weight
336.47
MOL File
143225-31-4.mol
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tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate Property

Melting point:
88.5-89.5 °C(Solv: hexane (110-54-3))
Boiling point:
484.7±45.0 °C(Predicted)
Density 
1.039±0.06 g/cm3(Predicted)
solubility 
soluble in Dichloromethane
form 
Solid
pka
12.07±0.46(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate Chemical Properties,Usage,Production

Uses

1,1-Dimethylethyl Ester [(1S,2S)-2-Hydroxy-3-[(2-methylpropyl)amino]-1-(phenylmethyl)propyl]carbamic Acid is an intermediate in the synthesis of 2-epi-Darunavir (D193530), which is a stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor

tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate Suppliers

HangZhou YuHao Chemical Technology Co., Ltd.
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Jinan blalong chemical co. LTD
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143225-31-4, tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamateRelated Search:


  • tert-butyl ((2S,3S)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate
  • Fosamprenavir Impurity 4
  • Fosamprenavir Impurity 6
  • Carbamic acid, N-[(1S,2S)-2-hydroxy-3-[(2-methylpropyl)amino]-1-(phenylmethyl)propyl]-, 1,1-dimethylethyl ester
  • 1,1-Dimethylethyl Ester [(1S,2S)-2-Hydroxy-3-[(2-methylpropyl)amino]-1-(phenylmethyl)propyl]carbamic Acid
  • FosamprevirImpurity4
  • 143225-31-4