3-IODO-1H-PYRROLO[3,2-C]PYRIDINE
- Product Name
- 3-IODO-1H-PYRROLO[3,2-C]PYRIDINE
- CAS No.
- 877060-47-4
- Chemical Name
- 3-IODO-1H-PYRROLO[3,2-C]PYRIDINE
- Synonyms
- 3-IODO-5-AZAINDOLE;3-Iodo-1H-pyrrolo[3,2-c]pyridin;3-IODO-1H-PYRROLO[3,2-C]PYRIDINE;1H-Pyrrolo[3,2-c]pyridine, 3-iodo-
- CBNumber
- CB9346963
- Molecular Formula
- C7H5IN2
- Formula Weight
- 244.03
- MOL File
- 877060-47-4.mol
3-IODO-1H-PYRROLO[3,2-C]PYRIDINE Property
- Melting point:
- 178-179℃
- Boiling point:
- 380.5±22.0 °C(Predicted)
- Density
- 2.082
- storage temp.
- 2-8°C(protect from light)
- pka
- 13.70±0.40(Predicted)
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- W9006
- Product name
- 3-Iodo-1H-pyrrolo[3,2-c]pyridine
- Packaging
- 5g
- Price
- $759
- Updated
- 2021/12/16
- Product number
- 124809
- Product name
- 3-Iodo-5-azaindole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $858
- Updated
- 2021/12/16
- Product number
- A468942
- Product name
- 3-Iodo-5-azaindole
- Purity
- 95%
- Packaging
- 100mg
- Price
- $17
- Updated
- 2021/12/16
- Product number
- A468942
- Product name
- 3-Iodo-5-azaindole
- Purity
- 95%
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
- Product number
- A468942
- Product name
- 3-Iodo-5-azaindole
- Purity
- 95%
- Packaging
- 1g
- Price
- $58
- Updated
- 2021/12/16
3-IODO-1H-PYRROLO[3,2-C]PYRIDINE Chemical Properties,Usage,Production
Synthesis
271-34-1
877060-47-4
General procedure for the synthesis of 3-iodo-5-azaindole from 5-azaindole: Potassium hydroxide (KOH, 10.39 g, 185.5 mmol, 3.8 eq.) was added to a solution of 1H-pyrrolo[3,2-c]pyridine (5.76 g, 48.8 mmol, 1.0 eq.) in N,N-dimethylformamide (DMF, 30 mL). The reaction mixture was stirred at room temperature for 15 minutes. Subsequently, the reaction mixture was cooled to 0°C and a solution of iodine (I2, 12.4 g, 48.8 mmol, 1.0 eq.) in DMF (15 mL) was slowly added. After continuing to stir at room temperature for 15 min, the reaction mixture was poured into water to quench the reaction. The precipitate was separated by filtration and the solid was washed well with deionized water. Finally, the resulting yellow solid was dried under vacuum to afford 3-iodo-1H-pyrrolo[3,2-c]pyridine (9.9 g, 83% yield).
References
[1] Synthesis, 2005, # 20, p. 3581 - 3588
[2] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 7, p. 2056 - 2060
[3] Patent: WO2018/11628, 2018, A1. Location in patent: Paragraph 00308
[4] Organic and Biomolecular Chemistry, 2011, vol. 9, # 14, p. 5129 - 5136
3-IODO-1H-PYRROLO[3,2-C]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-IODO-1H-PYRROLO[3,2-C]PYRIDINE manufacturers
- Product
- 3-IODO-1H-PYRROLO[3,2-C]PYRIDINE 877060-47-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg; 2kg;10kg; 100kg
- Release date
- 2019-08-30