ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE

Product Name: ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE
CAS No.: 6935-44-0
Chemical Name: ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE
Synonyms: AKOS UB-20070;RARECHEM AK ML 0354;ETHYL-α-CYANO-4-HYDROXYCINNAMATE;-Ethyl 2-cyano-3-(4-hydroxyphenyl);ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE;3-Piperazinecarboxamide,N,N-dimethyl-;ETHYL 2-CYANO-3-(4-HYDROXYPHENYL)ACRYLATE;(E)-Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate;methyl (E)-2-cyano-3-(4-hydroxyphenyl)acrylate;ethyl (E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoate
CBNumber: CB9349146
Molecular Formula: C12H11NO3
Formula Weight: 217.22
MOL File: 6935-44-0.mol

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ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE Property

Melting point:: 180-182°C
Boiling point:: 381.8±32.0 °C(Predicted)
Density: 1.241±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: Solid
pka: 7.42±0.15(Predicted)
Appearance: Light yellow to yellow Solid

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2916120090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Apolloscientific

Product number: OR15088
Product name: Ethyl2-cyano-3-(4-hydroxyphenyl)acrylate
Packaging: 1g
Price: $82
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4937-1-X4
Product name: Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate
Packaging: 1g
Price: $96
Updated: 2021/12/16

Matrix Scientific

Product number: 045898
Product name: Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate
Purity: >95%
Packaging: 500mg
Price: $118
Updated: 2021/12/16

Matrix Scientific

Product number: 045898
Product name: Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate
Purity: >95%
Packaging: 1g
Price: $151
Updated: 2021/12/16

AK Scientific

Product number: 0701AC
Product name: (E)-Ethyl2-cyano-3-(4-hydroxyphenyl)acrylate
Packaging: 500mg
Price: $209
Updated: 2021/12/16

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ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE Chemical Properties,Usage,Production

Chemical Properties

Light-yellow crystalline powder

Synthesis

123-08-0

105-56-6

42205-38-9

GENERAL METHODS: 5 mmol of p-hydroxybenzaldehyde was added to a round-bottomed flask with 5 mmol of ethyl cyanoacetate, 25 mg of polymer-loaded catalyst (0.5 mol% substrate) and 5 mL of anhydrous ethanol, and the reaction was stirred at room temperature. The reaction process was monitored by silica gel thin layer chromatography (TLC) with hexane-ethyl acetate (10:1) as eluent. Upon completion of the reaction, the reaction mixture was filtered using filter paper and the catalyst on the filter paper was washed several times with ethanol. The washings and filtrates were combined and the product was isolated after concentration under reduced pressure. Typically, the products were of high purity and did not require further purification. All the products were reported in literature and characterized by melting point determination, Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance hydrogen spectroscopy (1H NMR).

References

[1] Tetrahedron Letters, 2014, vol. 55, # 15, p. 2352 - 2354
[2] Synlett, 2016, vol. 27, # 9, p. 1433 - 1437
[3] Tetrahedron, 2000, vol. 56, # 47, p. 9357 - 9364
[4] Synthetic Communications, 2003, vol. 33, # 5, p. 783 - 788
[5] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010, vol. 49, # 3, p. 390 - 393

ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE Suppliers

China 44 Germany 3 India 1 United Kingdom 3 United States 8 Global 59

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6935-44-0, ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATERelated Search:

CDC ETHYL 3-(1,3-BENZODIOXOL-5-YL)-2-CYANOACRYLATE ISOBUTYL ALPHA-CYANO-3,4-METHYLENEDIOXYCINNAMATE ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE 2-(1-THIENYL)ETHYL 3,4-DIHYDROXYBENZYLIDENECYANOACETATE 2-(1-THIENYL)ETHYL-3,4-DIHYDROXYBENZYLIDENE-CYANOACETATE ETHYL 2-CYANO-3-(4-METHOXYPHENYL)ACRYLATE AKOS BBS-00008191 AURORA 7422 ETHYL 3-(4-((4'-NITROBENZYLOXY)PHENYL)PROP-2-ENOATE-2-NITRILE AURORA 9319 AURORA 11192 AKOS USSH-4110295 AURORA 5353 AURORA 5599 AURORA 6380 RARECHEM AL BR 0257 RARECHEM AL BR 0238

AKOS UB-20070

methyl (E)-2-cyano-3-(4-hydroxyphenyl)acrylate

ETHYL 2-CYANO-3-(4-HYDROXYPHENYL)ACRYLATE

ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE

RARECHEM AK ML 0354

ethyl (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoate

Ethyl 2-cyano-3-(4-hydroxyphenyl)prop-2-enoate, 4-(2-Cyano-3-ethoxy-3-oxoprop-1-en-1-yl)phenol

(E)-Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate

-Ethyl 2-cyano-3-(4-hydroxyphenyl)

ETHYL-α-CYANO-4-HYDROXYCINNAMATE

2-Propenoic acid, 2-cyano-3-(4-hydroxyphenyl)-, ethyl ester

3-Piperazinecarboxamide,N,N-dimethyl-

ethyl (E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoate

2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid ethyl ester

6935-44-0