4-Bromo-3-fluorotoluene

Product Name: 4-Bromo-3-fluorotoluene
CAS No.: 452-74-4
Chemical Name: 4-Bromo-3-fluorotoluene
Synonyms: 4-Bromo-3-fL;4-Bromo-3-flurotoluene;4-BROMO-3-FLUOROTOLUENE;3-FLUORO-4-BROMO-TOLUONE;3-FLUORO-4-BROMO-TOLUENE;Trelagliptin Impurity 95;4-Bromo-3-fluorotoluene >4-Bromo-3-fluorotoluene 98%;4-Bromo-3-fluorotoluene,98+%;4-BroMo-3-fluorotoluene, 98% 5GR
CBNumber: CB9362673
Molecular Formula: C7H6BrF
Formula Weight: 189.02
MOL File: 452-74-4.mol

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4-Bromo-3-fluorotoluene Property

Boiling point:: 95 °C/50 mmHg (lit.)
Density: 1.494 g/mL at 25 °C (lit.)
refractive index: n20/D 1.53(lit.)
Flash point:: 95 °F
storage temp.: Sealed in dry,Room Temperature
form: Liquid
Specific Gravity: 1.494
color: Clear light yellow
BRN: 2500154
InChI: InChI=1S/C7H6BrF/c1-5-2-3-6(8)7(9)4-5/h2-4H,1H3
InChIKey: SLFNGVGRINFJLK-UHFFFAOYSA-N
SMILES: C1(Br)=CC=C(C)C=C1F
CAS DataBase Reference: 452-74-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 10-36/37/38
Safety Statements: 26-37/39-16
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 3
PackingGroup: III
HS Code: 29039990
Storage Class: 3 - Flammable liquids
Hazard Classifications: Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B1935
Product name: 4-Bromo-3-fluorotoluene
Purity: >94.0%(GC)
Packaging: 5g
Price: $27
Updated: 2026/04/30

TCI Chemical

Product number: B1935
Product name: 4-Bromo-3-fluorotoluene
Purity: >94.0%(GC)
Packaging: 25g
Price: $99
Updated: 2026/04/30

TRC

Product number: B684745
Product name: 4-Bromo-3-fluorotoluene
Packaging: 10g
Price: $140
Updated: 2021/12/16

TRC

Product number: B684745
Product name: 4-Bromo-3-fluorotoluene
Packaging: 50g
Price: $415
Updated: 2021/12/16

Matrix Scientific

Product number: 001759
Product name: 4-Bromo-3-fluorotoluene
Purity: 98%
Packaging: 25g
Price: $17
Updated: 2021/12/16

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4-Bromo-3-fluorotoluene Chemical Properties,Usage,Production

Chemical Properties

colorless to light yellow liqui

Uses

4-Bromo-3-fluorotoluene may be used in the preparation of 1-(4-cyano-3- fluorobenzyl)-5-imidazolecarboxaldehyde and 1-bromo-4-bromomethyl-2-fluorobenzene.

Uses

4-Bromo-3-fluorotoluene is used in the synthesis of S-trityl-L-cysteine based inhibitors that show potent antitumor activity in lung cancer models. Chemical reagent for organic synthesis.

General Description

4-Bromo-3-fluorotoluene (1-bromo-2-fluoro-4-methylbenzene) is an aryl fluorinated building block. Synthesis of 4-bromo-3-fluorotoluene from o-nitro-p-toluidine (Fast Red Base GL), via diazo reaction at high temperature, Sandmeyer reaction, reduction and Schiemann reaction has been reported. Its density and refractive index have been determined.

Synthesis

the preparation method of a 4-Bromo-3-fluorotoluene, it is characterized in that: 4-amino-3-toluene fluoride hydrobromate, Hydrogen bromide, water drips Sodium Nitrite/water down at-10-10 ℃ and carries out diazotization, reaction solution joins in cuprous bromide/hydrobromic solution, and bromination under the normal temperature was reacted 0.5-2 hour, separate, purifying obtains target product 4-Bromo-3-fluorotoluene.

References

[1] Method for preparing 4-bromine-3-fluorine methylbenzene. CN1274650C

4-Bromo-3-fluorotoluene Preparation Products And Raw materials

Raw materials

Preparation Products

2-Fluoro-4-methylphenylboronic acid

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4-Bromo-3-fluorotoluene Suppliers

Americas 1 Belgium 2 Canada 1 China 280 Europe 4 France 1 Germany 5 India 9 Italy 1 Japan 4 Slovakia 1 Switzerland 4 Ukraine 1 United Kingdom 26 United States 46 Global 386

JIANGYIN RUISHIPHARM CO.,LIMITED

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Wuhan WinYuanBei Trading Company

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Shandong Zhishang Chemical Co. LTD

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FUXIN QINGJISHENG SCIENCE AND TECHNOLOGY CO.,LID

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Hubei Xinliheng Chemical Co., Ltd

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Cangzhou Enke Pharma Tech Co.,ltd.

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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
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View Lastest Price from 4-Bromo-3-fluorotoluene manufacturers

Changzhou waston chemical technology Co.,Ltd

Product: 4-Bromo-3-fluorotoluene 452-74-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: As your request
Release date: 2025-07-16

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Bromo-3-fluorotoluene 452-74-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-25

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Bromo-3-fluorotoluene 452-74-4
Price: US $0.00-0.00/KG
Min. Order: 50mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-08

452-74-4, 4-Bromo-3-fluorotolueneRelated Search:

2-Methylbenzotrifluoride Ethyl bromodifluoroacetate Tosufloxacin tosylate 4-Bromotoluene 3-Fluorobenzotrifluoride 3-Bromo-5-fluorobenzotrifluoride Benzotrifluoride 4-Bromo-3-fluorobenzotrifluoride 4-BROMO-2-CHLORO-5-FLUOROTOLUENE 99 4-BROMO-2,3,5,6-TETRAFLUOROBENZOTRIFLUORIDE 4-Bromo-2,3,5,6-tetrafluorotoluene 3-FLUORO-4-BROMO-ACETOPHENONE 4-Bromo-3-fluorobenzoic acid 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID 4,4'-DIBROMOOCTAFLUOROBIPHENYL 3-Bromobenzotrifluoride 4-Bromo-3-nitrobenzotrifluoride 5-Bromo-2-chlorobenzotrifluoride

4-BROMO-3-FLUOROTOLUENE

3-FLUORO-4-BROMO-TOLUENE

4-Bromo-3-fluorotoluene,98+%

4-Bromo-3-fluorotoluene 98%

4-Bromo-3-fluoro-1-methylbenzene

4-Bromo-3-flurotoluene

3-FLUORO-4-BROMO-TOLUONE

4-BroMo-3-fluorotoluene, 98% 5GR

Benzene,1-broMo-2-fluoro-4-Methyl-

4-Bromo-3-fluorotoluene &gt

4-Bromo-3-fL

Trelagliptin Impurity 95

4-Propyl-3'-Fluorobiphenyl-4'-Boronic Acid

452-74-4

C7H6BrF

ARYL HALIDE

C7

Aryl

Building Blocks

Organic Building Blocks

Halogenated Hydrocarbons

Aryl

C7

Halogenated Hydrocarbons

Halogen toluene

Miscellaneous

Bromine Compounds

Fluorine Compounds

Fluorin-contained toluene series

blocks

Bromides

FluoroCompounds

Aromatic Halides (substituted)