4-ACETYL-2-METHOXYPHENYL ACETATE
- Product Name
- 4-ACETYL-2-METHOXYPHENYL ACETATE
- CAS No.
- 54771-60-7
- Chemical Name
- 4-ACETYL-2-METHOXYPHENYL ACETATE
- Synonyms
- Pemetrexed Impurity 75;LABOTEST-BB LT00012613;4-ACETYLACETOVANILLONE;4-ACETOXY-3-METHOXYACETOPHENONE;4-ACETYL-2-METHOXYPHENYL ACETATE;4-Acethyl-2-methoxyphenyl acetete;Phenol, 4-acetyl-2-methoxy, acetate;1-(4-ACETOXY-3-METHOXYPHENYL)ETHANONE;Acetic acid 4-acetyl-2-methoxyphenyl ester;1-[4-(acetyloxy)-3-Methoxyphenyl]-Ethanone
- CBNumber
- CB9369001
- Molecular Formula
- C11H12O4
- Formula Weight
- 208.21
- MOL File
- 54771-60-7.mol
4-ACETYL-2-METHOXYPHENYL ACETATE Property
- Melting point:
- 54-57 °C(lit.)
- Boiling point:
- 294.7±25.0 °C(Predicted)
- Density
- 1.140±0.06 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- yellow solid
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A189025
- Product name
- 4-Acetyl-2-methoxyphenylAcetate
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- A189025
- Product name
- 4-Acetyl-2-methoxyphenylAcetate
- Packaging
- 5g
- Price
- $280
- Updated
- 2021/12/16
- Product number
- FA70401
- Product name
- 4-Acetoxy-3-methoxyacetophenone
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA70401
- Product name
- 4-Acetoxy-3-methoxyacetophenone
- Packaging
- 2g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FA70401
- Product name
- 4-Acetoxy-3-methoxyacetophenone
- Packaging
- 5G
- Price
- $150
- Updated
- 2021/12/16
4-ACETYL-2-METHOXYPHENYL ACETATE Chemical Properties,Usage,Production
Definition
ChEBI: 4-acetyl-2-methoxyphenyl acetate is an acetate ester that is phenylacetate substituted by an acetyl group at position 4 and a methoxy group at position 2 respectively. It is a member of acetophenones, a monomethoxybenzene and a member of phenyl acetates.
Synthesis
64-19-7
498-02-2
54771-60-7
General procedure for the synthesis of 1-(4-acetoxy-3-methoxyphenyl)ethanone from glacial acetic acid and vanillylacetophenone: reference to Example 1. Preparation of intermediate (1): 4-acetyl-2-methoxyphenyl acetate (1). 500 mg (3 mM) of acetylisopropyl ketone was dissolved in 20 mL of THF and 0.5 mL of pyridine and 0.6 mL of anhydrous acetic acid were added. The reaction mixture was stirred at room temperature for 3 hours. After completion of the reaction, the product was extracted with diethyl ether and the organic phase was dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography with hexane:ethyl acetate (4:1) as mobile phase to give 4-acetyl-2-methoxyphenyl acetate (1; 625 mg) as white solid. Melting point: 58.7 °C; 1H NMR (CDCl3): δ 7.60 (d, 1H, J = 1.8 Hz, H-3), 7.55 (dd, 1H, J = 1.8, 8.2 Hz, H-5), 7.12 (d, 1H, J = 8.2 Hz, H-6), 3.89 (s, 3H, OCH3), 2.59 (s, 3H, OCOCH3) and 2.33 (s, 3H, COCH3).
References
[1] Patent: WO2008/41826, 2008, A1. Location in patent: Page/Page column 17; 35-36
4-ACETYL-2-METHOXYPHENYL ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-ACETYL-2-METHOXYPHENYL ACETATE manufacturers
- Product
- 4-ACETYL-2-METHOXYPHENYL ACETATE 54771-60-7
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-08-08