ChemicalBook > CAS DataBase List > SC 19220

SC 19220

Product Name
SC 19220
CAS No.
19395-87-0
Chemical Name
SC 19220
Synonyms
SC 19220;2-acetylhydrazide 10(11h)-carboxylic acid;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid;N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide;8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10[11H]-CARBOXY-(2-ACETYL)HYDRAZIDE;8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE;8-CHLORO-DIBENZO[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE;Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide;8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacid,2-acetylhydrazide;2-Acetylhydrazide 10(11H)-carboxylic acid, 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid
CBNumber
CB9372348
Molecular Formula
C16H14ClN3O3
Formula Weight
331.75
MOL File
19395-87-0.mol
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SC 19220 Property

Melting point:
190-191 °C (lit.)
storage temp. 
Store at RT
solubility 
DMSO: 10 mg/mL, soluble
form 
solid
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S3065
Product name
SC 19220
Purity
≥98% (HPLC), solid
Packaging
10mg
Price
$82.4
Updated
2024/03/01
Sigma-Aldrich
Product number
S3065
Product name
SC 19220
Purity
≥98% (HPLC), solid
Packaging
50mg
Price
$832
Updated
2023/01/07
Cayman Chemical
Product number
14060
Product name
SC 19220
Purity
≥96%
Packaging
1mg
Price
$20
Updated
2024/03/01
Cayman Chemical
Product number
14060
Product name
SC 19220
Purity
≥96%
Packaging
5mg
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
14060
Product name
SC 19220
Purity
≥96%
Packaging
10mg
Price
$146
Updated
2024/03/01
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SC 19220 Chemical Properties,Usage,Production

Uses

SC 19220 is a selective EP1?receptor antagonist.

Uses

SC 19220 was used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection in rat cortical cultures.

Definition

ChEBI: N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide is an aromatic ether.

Biological Activity

Selective EP 1 receptor antagonist (IC 50 = 6.7 μ M for inhibition of [ 3 H]-PGE 2 binding to EP 1 transfected COS cells).

Biochem/physiol Actions

SC 19220 is a competitive antagonist of prostaglandin E receptors. It competes with PGE2 in regulating vesicourethral motility and increases the bladder capacity of rats. It inhibits the contraction of smooth muscles in response to prostaglandins E2 and F2α. SC 19220 also inhibits the formation of osteoclasts induced by vitamin D3, parathyroid hormone, IL-11 and IL-6.

storage

Store at RT

SC 19220 Preparation Products And Raw materials

Raw materials

Preparation Products

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SC 19220 Suppliers

CHINA 34 Germany 1 Switzerland 1 United Kingdom 2 United States 7 Global 45
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24023
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27996
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4164
Advantage
58

19395-87-0, SC 19220Related Search:

Pinadoline SC-51089 SC 19220 SC-51322

  • 8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10[11H]-CARBOXY-(2-ACETYL)HYDRAZIDE
  • 8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE
  • 8-CHLORO-DIBENZO[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE
  • SC 19220
  • 2-acetylhydrazide 10(11h)-carboxylic acid
  • 2-Acetylhydrazide 10(11H)-carboxylic acid, 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid
  • 8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacid,2-acetylhydrazide
  • 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid
  • N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
  • Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
  • 19395-87-0
  • C16H14N3O3Cl